Lucie Peirera

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Crossovers (COs) are essential for the completion of meiosis in most species and lead to new allelic combinations in gametes. Two pathways of meiotic crossover formation have been distinguished. Class I COs, which are the major class of CO in budding yeast, mammals, Caenorhabditis elegans, and Arabidopsis, depend on a group of proteins called ZMM and rely(More)
Neurofibromatosis Type 1 (NF1) is an autosomal dominant genetically inherited condition caused by heterozygous mutations of the NF1 gene1. Almost half of all cases are attributed to de-novo mutations. The disease is characterized by wide clinical variability among unrelated individuals, individuals within a single family, and even in a single individual at(More)
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