Lucia Cachafeiro

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BACKGROUND The previously published "Dose Response Multicentre International Collaborative Initiative (DoReMi)" study concluded that the high mortality of critically ill patients with acute kidney injury (AKI) was unlikely to be related to an inadequate dose of renal replacement therapy (RRT) and other factors were contributing. This follow-up study aimed(More)
We have read the commentary by Berger and Que [1] about our paper [2]. We are thankful to them for their comments; we would like to clarify some points. First, the crude mortality rate, duration of mechanical ventilation, and renal dysfunction cannot be solely attributed to the resuscitation protocol. In addition, other factors are involved, such as(More)
INTRODUCTION The use of urinary output and vital signs to guide initial burn resuscitation may lead to suboptimal resuscitation. Invasive hemodynamic monitoring may result in over-resuscitation. This study aimed to evaluate the results of a goal-directed burn resuscitation protocol that used standard measures of mean arterial pressure (MAP) and urine(More)