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Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene
The Cyclin E1 gene (CCNE1) is an ideal model to explore the mechanisms that control the transcription of cell cycle-regulated genes whose expression rises transiently before entry into S phase.Expand
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Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression.
Class II major histocompatibility (MHC-II) genes are prototype targets of IFN-gamma. IFN-gamma activates the expression of the non-DNA-binding master regulator of MHC-II, class II transactivatorExpand
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Methylation specifies distinct estrogen-induced binding site repertoires of CBP to chromatin.
Multiple signaling pathways ultimately modulate the epigenetic information embedded in the chromatin of gene promoters by recruiting epigenetic enzymes. We found that, in estrogen-regulated geneExpand
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Dual role of the arginine methyltransferase CARM1 in the regulation of c‐Fos target genes
Fos proteins, the prototypic members of basic region‐leucine zipper (bZIP) transcription factors, bind to other bZIP proteins to form the activator protein‐1 (AP‐1) complex, which regulates theExpand
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CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity
The acetyltransferases CBP and P300 have been implicated in myogenesis in mouse immortalized cell lines but these studies focused only on the expression of a handful of myogenic factors. Hence, theExpand
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Quand l’environnement du père influence l’expression génique chez l’enfant
> La reproduction dite sexuée consiste en la fusion d’un gamète mâle et d’un gamète femelle provenant de deux individus de types sexuels différents donnant naissance à un œuf ou zygote génétiquementExpand
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Régulation de la transcription par l'arginine méthyltransférase CARM1/PRMT4
Les enzymes de remodelage et de modification de la chromatine jouent un role majeur dans de nombreux processus biologiques et sont notamment primordiales au cours de la regulation de laExpand
[When the father's environment influences gene expression in the child].