Learn More
RNA polymerase II transcribes the physical ends of linear eukaryotic chromosomes into a variety of long non-coding RNA molecules including telomeric repeat-containing RNA (TERRA). Since TERRA discovery, advances have been made in the characterization of TERRA biogenesis and regulation; on the contrary its associated functions remain elusive. Most of the(More)
We study asymptotic behavior in a class of non-autonomous second order parabolic equations with time periodic unbounded coefficients in R × R d. Our results generalize and improve asymptotic behavior results for Markov semigroups having an invariant measure. We also study spectral properties of the realization of the parabolic operator u → A(t)u − ut in(More)
The telomeric transcriptome comprises multiple long non-coding RNAs generated by transcription of linear chromosome ends. In a screening performed in Schizosaccharomyces pombe, we identified factors modulating the cellular levels of the telomeric transcriptome. Among these factors, Cay1 is the fission yeast member of the conserved family of Cactins,(More)