Luboš Homola

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AIMS AND BACKGROUND Radiotherapy represents one of the basic therapeutic methods in treatment of localized carcinoma of the prostate. Optimal irradiation dose is the cornerstone of a successful treatment. Along with local control of the disease and overall survival of the patient, possible acute and long-term side effects need to be monitored very closely.(More)
Over the past few years, brachytherapy has become more and more common in the treatment of prostate cancer, largely thanks to the reduced amount of acute and chronic side effects. At the same time, brachytherapy also allows dose escalation, resulting in significant improvements in the treatment results. From August 2004 to June 2005, we irradiated 40(More)
BACKGROUND Over the past few years, brachytherapy has become more and more common in the treatment of prostate cancer. Part of the reason behind this growth in the use of brachytherapy for the treatment of organ-confined prostate cancer is the reduced amount of acute and chronic side effects. On the other hand, brachytherapy allows for dose escalation,(More)
Although being used for several decades, interstitial brachytherapy remains a modern radiotherapeutic method. Over the time, it has been highly improved, including the latest technologies. Its broad use has been facilitaed by the use of high dose rate (HDR) afterloadings. The method is fast and fairly inexpensive. Its prons include, in particular, a(More)
The popularity of permanent brachytherapy is now growing dramatically. The development of several new technologies has led to an improvement in dose distribution and results and can also return the patients to normal daily activities. The role of permanent brachytherapy in the treatment of localized prostate carcinoma is described in the present article.(More)
To examine evidence of positive antibodies against immunogenic proteins of Anaplasma phagocytophilum in patients with other tick-borne infections and to diagnose possible co-infections, 412 serum specimens were tested by immunoblotting using three specific Anaplasma antigens: surface proteins p44 and Asp62 and outer membrane protein A (OmpA). In total, 284(More)
The author revised the conclusion drawn from his former experiments and recognized a complex phenomenon that he named osmofiltration. This phenomenon occurs by way of the inhibition of the diffusion within a micro-gap bordering the experimental membrane in the model. It may have a significance as a basic biological phenomenon in similar biological(More)
BACKGROUND Prostate cancer is an illness with a high incidence, especially among older men. The choice of a treatment option among men above 75 years is, however, not clear. Radical prostatectomy in this age group is connected with a relatively high morbidity. A further possibility of curative treatment is radiotherapy which can be administered in the form(More)
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