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OBJECTIVE To determine whether 25OH-D levels in the follicular fluid (FF) of infertile women undergoing IVF demonstrate a relationship with IVF cycle parameters and outcome, hypothesizing that levels of 25OH-D in body fluids are reflective of vitamin repletion status. DESIGN Prospective cohort study. SETTING Academic tertiary care center. PATIENT(S)(More)
OBJECTIVE To investigate the predictors of postthaw blastomere survival and the relationship of blastomere survival to the outcome of frozen-thawed embryo transfer (FET) cycles. DESIGN Retrospective study. SETTING An IVF unit in a tertiary care facility. PATIENT(S) Infertile women undergoing FET cycles with embryos cryopreserved on day 3(More)
OBJECTIVE To determine the significance of prestimulation ovarian cysts on the response to controlled ovarian hyperstimulation and the outcome of IVF. DESIGN Retrospective study. SETTING In vitro fertilization unit in an academic center. PATIENT(S) One hundred thirty-seven patients undergoing IVF. INTERVENTION(S) The outcome of 71 patients who had(More)
OBJECTIVES To investigate whether a diagnosis of diminished ovarian reserve (DOR) in premenopausal years has adverse implications for skeletal health and quality of life. DESIGN This was a cross-sectional study of infertile, albeit healthy, mid-reproductive-age women (younger than 42 y) attending an academic infertility practice. RESULTS Eighty-nine(More)
OBJECTIVE To assess overall knowledge, attitudes, and practices related to conception and fertility among reproductive-age women in the United States. DESIGN Online survey of a cross-sectional sample of 1,000 women. SETTING United States, March 2013. PATIENT(S) Women aged 18-40 years. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Knowledge,(More)
A case series of eight cycles of in-vitro fertilization (IVF) in five women diagnosed with malignant disorders is presented. These patients chose to defer definitive treatment for a chance for preservation of potential fertility. The response of these patients to ovarian stimulation, and the outcome, was compared with 17 IVF cycles in 12 age-matched(More)
OBJECTIVE To assess effects of vitamin D and Calcium (Ca) on hormonal and metabolic milieu of polycystic ovary syndrome (PCOS). DESIGN Single arm open label trial. METHODS Twelve overweight and vitamin D deficient women with PCOS underwent a 2 hour oral glucose tolerance testing at baseline and following 3-month supplementation with vitamin D (daily(More)
BACKGROUND In-vitro fertilization (IVF) with blastocyst as opposed to cleavage stage embryos has been advocated to improve success rates. Limited information exists on which to predict which patients undergoing blastocyst embryo transfer (BET) will achieve pregnancy. This study's objective was to evaluate the predictive value of patient and cycle(More)
BACKGROUND We explored the relevance of blood type to ovarian reserve, as reflected by early follicular phase FSH levels. METHODS For this cross-sectional observational study, early follicular phase serum levels of FSH (mIU/ml) and estradiol (E2, pg/ml), and information on blood type (A, B, AB and O) and patient age were procured for female patients, ≤ 45(More)
OBJECTIVE To investigate if a diagnosis of diminished ovarian reserve (DOR) is associated with a differential gene profile of ovarian granulosa cells (GCs) in infertile women undergoing in vitro fertilization (IVF). DESIGN Prospective Cohort Study. SETTING Academic IVF Program. PATIENTS Infertile women <38 years were prospectively enrolled into 2(More)