Lubica Prochazkova

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Prolonged-release fampridine (fampridine PR) is a potassium channel blocker that improves conductivity of signal on demyelinated axons in central nervous system. Fampridine PR has been approved to improve speed of walking in patients with multiple sclerosis. This statement provides a brief summary of data on fampridine PR and recommendations on practical(More)
OBJECTIVE The paper is concerned with the problem of extraction of foreign metal bodies, which remained after a perforating injury in the patient's lens. The authors discuss early and late extraction of the opacifying lens. MATERIAL AND METHODS In three successive accidents of young men (22-34 years) the authors compare the fate of intralenticular metal(More)
BACKGROUND Many neurological diseases are connected with the dysfunction of blood-CSF barrier. The quantitative determination of CSF proteins has already been used in the diagnosis of barrier impairments and inflammatory diseases of the central nervous system. PATIENTS Serum and CSF, totaling 264 samples, were obtained from 15 controls and 117 patients(More)
INTRODUCTION Diabetic macular edema (DME) is the most common cause of a visus dicrease in patients suffering type 2 diabetes. DME originates in abnormal macula capillars permeability. This study presents the findings of observing patients with DME after by micropulse laser therapy with the wavelength of 577 nm. METHODS The study covers 23 eyes of 15(More)
OBJECTIVES The aim of the present study was to assess cerebrospinal fluid (CSF) levels of malondialdehyde (MDA), F2 isoprostanes (8-iso-PGF2α) and total antioxidant status (TAS) in relapsing-remitting (RR) and secondary progressive (SP) course of MS and neurological controls. These parameters were correlated with brain tissue damage parameters -(More)
There is about 30% higher risk of the myocardial infarction in patients diagnosed with multiple sclerosis (MS) than in people without MS. Increased risk of cardiovascular disease development positively correlates with levels of serum markers of an endothelial dysfunction, and may give rise to a global cerebral hypoperfusion. It appears that these(More)
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