Luana Paredes Leite

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Cardiotocography (CTG) lacks reliability and reproducibility and these problems are believed to be overcome by computer analysis. In this article we describe a system developed for routine clinical automated CTG analysis based on a low cost personal computer. Presently the system has processed 70 ten minute tracings. Fetal heart rate baseline,(More)
OBJECTIVE To identify patients with gastroesophageal reflux disease (GERD) who, despite omeprazole 20 mg b.i.d., demonstrate continued abnormal gastric acid secretion. METHODS Eighty-eight patients with GERD completed ambulatory gastric and esophageal pH monitoring for persistent symptoms on omeprazole 20 mg b.i.d.. Seventeen (19%) demonstrated abnormal(More)
UNLABELLED Patients with gastroesophageal reflux disease (GERD) who remain symptomatic despite receiving a moderate dose of a proton pump inhibitor need accurate assessment to determine who will respond to high doses of the drug or even need surgery. AIM To determine if prolonged ambulatory pH monitoring performed in patients with persistent symptoms(More)
Successful omeprazole therapy in patients with symptomatic gastroesophageal reflux (GER) refractory to treatment with H2-receptor antagonists has often been reported. In contrast, successful treatment of GER by H2-receptor antagonists in patients resistant to the acid-suppressing effects of omeprazole is rarely reported. We describe two patients who(More)
The relationship between the birth weights of the mother and her infant was evaluated in a sample of 106 women consecutively delivered of a single live birth. Women were included in the study if their birth weight was available in hospital files or from another reliable source. Women that were themselves a twin or had diseases complicated the course of the(More)
Knowledge of the fetal circulation is a prerequisite for understanding the physiological behaviour of the developing fetus. In this overview dealing with Colour and Power Doppler ultrasound findings in the first trimester of pregnancy and its pathophysiological background, we aim to report on the methodological aspects, normal blood flow waveform patterns,(More)
BACKGROUND Spontaneous rises in intragastric pH are a common phenomenon in patients and normal subjects who undergo prolonged ambulatory pH monitoring; however, controversy exists over their etiology. Some investigators have postulated that these events are secondary to duodenogastric bile reflux (DGBR), and others have implicated increased salivation or(More)
OBJECTIVE To determine the effect of decreasing time intervals between acid exposures on the sensitivity of the esophageal mucosa. METHODS Ten healthy subjects with no history of gastroesophageal reflux disease who were symptomatic during a modified Bernstein acid infusion test were recruited for the study. Hydrochloric acid solutions of pH 3, 2, and 1(More)
OBJECT To assess the effect of acid infusion on the response of normal subjects to progressive intra-oesophageal balloon distension (IOBD). METHODS Twenty-one volunteers underwent slow IOBD. Subjects were asked to indicate the first perception of sensation (S1) and the onset of pain (S2), balloon volumes being recorded at both points. A 15-min infusion of(More)