Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications.
OBJECTIVE Type 2 diabetes is characterized by impaired insulin secretion in response to increased metabolic demand. This defect in beta-cell compensation seems to result from the interplay between… (More)
In this article, Figure 2F was incorrect. The correct panel is shown below. The authors sincerely apologise for this error.
Islet Biology Laboratory, Centre for Biomolecular Interactions Bremen, University of Bremen, Leobener Straße NW2, Room B2080, PO Box 330440, 28359 Bremen, Germany, Larry L. Hillblom Islet Research… (More)
Aims/hypothesisIn obesity, beta cells activate compensatory mechanisms to adapt to the higher insulin demand. Interleukin-1 receptor antagonist (IL-1Ra) prevents obesity-induced hyperglycaemia and is… (More)
Type 2 diabetes manifests when the β-cell fails to secrete sufficient amounts of insulin to maintain normoglycemia and undergoes apoptosis. The disease progression results from an interplay of… (More)
Recent evidence suggests that IL-1beta-mediated glucotoxicity plays a critical role in type 2 diabetes mellitus. Although previous work has shown that inhibiting IL-1beta can lead to improvements in… (More)
Aims/hypothesisChronic hyperglycaemia promotes the progressive failure of pancreatic beta cells in patients with type 2 diabetes mellitus, a clinically highly relevant phenomenon known as… (More)
The diabetes is mainly treated by the oral administration of western medicines at present. Despite their rapid curative effect, there have been still many reports for the western medicines about… (More)
The methods and technique of inducing polyploid plants of Platycodon grandiflorum were done. Many autotetraploid plant lines were induced by colchicine in vitro successfully. The identification of… (More)
The above-cited article has been retracted by the American Diabetes Association (ADA), the publisher of Diabetes. This article was previously the subject of an expression of concern in the August… (More)