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Brain tumors are the most common solid tumors of childhood, and pilocytic astrocytomas (PA) are the most common central nervous system tumor in 5 to 19 year olds. Little is known about the genetic alterations underlying their development. Here, we describe a tandem duplication of approximately 2 Mb at 7q34 occurring in 66% of PAs. This rearrangement, which(More)
MapReduce has emerged as a popular method to process big data. In the past few years, however, not just big data, but fast data has also exploded in volume and availability. Examples of such data include sensor data streams, the Twitter Firehose, and Facebook updates. Numerous applications must process fast data. Can we provide a MapReduce-style framework(More)
Influence is a complex and subtle force that governs the dynamics of social networks as well as the behaviors of involved users. Understanding influence can benefit various applications such as viral marketing, recommendation, and information retrieval. However, most existing works on social influence analysis have focused on verifying the existence of(More)
A Content Based Image Retrieval System is a computer system for browsing, searching and retrieving images from a large database of digital images .Most common methods of image retrieval utilize some method of adding meta data such as captioning, keywords or description to the images so that retrieval can be performed over the annotation words. Content Based(More)
A scaling theory of double-gate interband tunnel field-effect transistors (TFETs) using a physics-based 2-D analytical model is presented. Ignoring the mobile charge in the channel, the electrostatic potential profile and electric field are analytically solved, and the current is calculated by integrating the band-to-band tunneling generation rate over the(More)
The capacity to respond to day length, photoperiodism, is crucial for flowering plants to adapt to seasonal change. The photoperiodic control of flowering in plants is mediated by a long-distance mobile floral stimulus called florigen that moves from leaves to the shoot apex. Although the proteins encoded by FLOWERING LOCUS T (FT) in Arabidopsis and its(More)
1. We investigated muscarinic receptors in the detrusor and mucosa of the human bladder body. Radioligand-binding studies with [(3)H]QNB were conducted using specimens collected from patients (36-77 years) with normal bladder function, undergoing surgery. For RT-PCR, biopsies of normal bladder were obtained from patients (30-88 years) undergoing check(More)
Lipoid proteinosis (OMIM 247100), also known as Urbach-Wiethe disease or hyalinosis cutis et mucosae, is a rare autosomal recessive disorder characterized by generalized thickening and scarring of the skin and mucosae. In 2002, the disorder was mapped to a locus on chromosome 1q21 and pathogenic mutations were identified in the ECM1 gene, which encodes for(More)
Floral transition in Arabidopsis is tightly controlled by complex genetic regulatory networks in response to endogenous and environmental flowering signals. SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) and SHORT VEGETATIVE PHASE (SVP), two key MADS-domain transcription factors, perceive these signals and function as antagonistic flowering regulators.(More)
Automatic topic discovery and tracking on web-shared videos can greatly benefit both web service providers and end users. Most of current solutions of topic detection and tracking were done on news and cannot be directly applied on web videos, because the semantic information of web videos is much less than that of news videos. In this paper, we propose a(More)