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Primary cultures of mouse astrocytes were used to investigate effects by chronic treatment (3-21 days) with fluoxetine (0.5-10 μM) on capacitative Ca(2+) influx after treatment with the SERCA inhibitor thapsigargin and on receptor agonist-induced increases in free cytosolic Ca(2+) concentration [Ca(2+)](i), determined with Fura-2. The agonists were the(More)
Studies on the pattern of geographic variation in bird vocalizations can facilitate the understanding of the evolutionary history of species and species differentiation. The Common Cuckoo (Cuculus canorus) is a non-passerine widely distributed in Eurasia, and its calls are not acquired through learning. Revealing the geographic pattern of Common Cuckoo(More)
Recently developed methods for fluorescence-activated cell sorting (FACS) of freshly-isolated brain cells from transgenic mice combining fluorescent signals with cell type-specific markers allow cell-type separation. Based upon previous observations in primary cultures of mouse astrocytes we treated transgenic mice tagged with a neuron-specific or an(More)
Previously, we reported that chronic treatment with fluoxetine increased gene expression of 5-hydroxytryptamine receptor 2B (5-HT2BR), cytosolic phospholipase 2α (cPLA2α), glutamate receptor, ionotropic kainate 2 (GluK2) and adenosine deaminase acting on RNA 2 (ADAR2), in cultured astrocytes and astrocytes freshly isolated from transgenic mice tagged with(More)
Few studies have examined the etiology of psychopathic traits in youth, and even fewer have tested whether the genetic and environmental influences underlying these traits differ for boys and girls. We tested for sex differences in the etiology of 3 trait dimensions-impulsivity, narcissism, and callous-unemotionality (CU)-previously found to underlie youth(More)
Despite increasing study of psychopathic traits in children and adolescents, evidence regarding the factor structure of these traits has been inconsistent across community, clinic-referred, and incarcerated samples. Empirical support exists for both 2-factor (Impulsivity-Conduct Problems and Callous-Unemotional) and 3-factor (Narcissism,(More)