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The spatial spread of the highly pathogenic avian influenza virus H5N1 and its long-term persistence in Asia have resulted in avian influenza panzootics and enormous economic losses in the poultry sector. However, an understanding of the regional long-distance transmission and seasonal patterns of the virus is still lacking. In this study, we present a(More)
Few studies have examined the etiology of psychopathic traits in youth, and even fewer have tested whether the genetic and environmental influences underlying these traits differ for boys and girls. We tested for sex differences in the etiology of 3 trait dimensions-impulsivity, narcissism, and callous-unemotionality (CU)-previously found to underlie youth(More)
Primary cultures of mouse astrocytes were used to investigate effects by chronic treatment (3-21 days) with fluoxetine (0.5-10 μM) on capacitative Ca(2+) influx after treatment with the SERCA inhibitor thapsigargin and on receptor agonist-induced increases in free cytosolic Ca(2+) concentration [Ca(2+)](i), determined with Fura-2. The agonists were the(More)
Epithelial-mesenchymal transition (EMT) is a fundamental process in embryonic development and organ formation. Aberrant regulation of EMT often leads to tumor progression. Changes in cell surface sialylation have recently been implicated in mediating EMT. Herein we report the visualization of dynamic changes of sialylation and glycoproteomic analysis of(More)
BACKGROUND The spatial spread of H5N1 avian influenza, significant ongoing mutations, and long-term persistence of the virus in some geographic regions has had an enormous impact on the poultry industry and presents a serious threat to human health. METHODS We applied phylogenetic analysis, geospatial techniques, and time series models to investigate the(More)
In the detection of ankle injuries, the Cumberland Ankle Instability Tool (CAIT) has been widely used. However, despite its validity and reliability as acclaimed by some therapists, certain inadequacies are still present due to the differences in judgements made by the physiotherapists and human subjects. This project investigates the possible use of the(More)
Studies on the pattern of geographic variation in bird vocalizations can facilitate the understanding of the evolutionary history of species and species differentiation. The Common Cuckoo (Cuculus canorus) is a non-passerine widely distributed in Eurasia, and its calls are not acquired through learning. Revealing the geographic pattern of Common Cuckoo(More)
The interaction between endocrine disruptor phthalic acid esters (PAEs) and human serum albumin (HSA) was studied by fluorescence spectroscopy and molecular modeling methods. The efficiency of energy transfer and the distance between HSA and PAEs were calculated. The results showed that all of the four kinds of PAEs could quench the intrinsic fluorescence(More)
Recently developed methods for fluorescence-activated cell sorting (FACS) of freshly-isolated brain cells from transgenic mice combining fluorescent signals with cell type-specific markers allow cell-type separation. Based upon previous observations in primary cultures of mouse astrocytes we treated transgenic mice tagged with a neuron-specific or an(More)