Luísa Castro

Learn More
A quaponics is a food production system that uses nutrient-rich water from fish culture to irrigate and fertilize plants. After the plants have absorbed the nutrients, the water is recirculated to the fish rearing tanks. This combination of aquaculture and hydroponics recycles both water and nutrients, resulting in an efficient use of resources. However,(More)
—An agglomerative hierarchical clustering method, which uses both spectral and spatial information for the aggrega-tion decision, is proposed here. The method is suitable for large multispectral images, provided that an unsupervised classification is previously applied. The method is tested on a synthetic image and on a satellite image of the coastal zone.
Phase precession is one of the most well known examples within the temporal coding hypothesis. Here we present a biophysical spiking model for phase precession in hippocampal CA1 which focuses on the interaction between place cells and local inhibitory interneurons. The model’s functional block is composed of a place cell (PC) connected with a local(More)
Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate phosphoribosyltransferase domain containing 1 (NAPRT1) are the main human NAD salvage enzymes. NAD regulates energy metabolism and cell signaling, and the enzymes that control NAD availability are linked to pathologies such as cancer and neurodegeneration. Here, we have screened normal and tumor(More)
Grid cells (GCs) in the medial entorhinal cortex (mEC) have the property of having their firing activity spatially tuned to a regular triangular lattice. Several theoretical models for grid field formation have been proposed, but most assume that place cells (PCs) are a product of the grid cell system. There is, however, an alternative possibility that is(More)
MOTIVATION Ebola virus causes high mortality hemorrhagic fevers, with more than 25 000 cases and 10 000 deaths in the current outbreak. Only experimental therapies are available, thus, novel diagnosis tools and druggable targets are needed. RESULTS Analysis of Ebola virus genomes from the current outbreak reveals the presence of short DNA sequences that(More)
The university is an equal opportunity/affirmative action institution providing programs and services to the people of Hawai'i without regard Introduction Aquaponics (the integration of aquaculture and hy-droponics) is a developing technology that serves as a model of sustainable food production. In a recirculating aquaponic system (RAS), liquid effluent(More)
R ecent cases of eosinophilic meningitis have drawn attention to a foodborne parasitic infection that occurs in Hawai'i, the Pacific Islands, southern and eastern Asia, and elsewhere. In late 2008, the Hawai'i Department of Health reported that four people on the island of Hawai'i were diagnosed with eosinophilic meningitis, secondary to rat lungworm(More)
Nicotinamide Adenine Dinucleotide (NAD) levels are essential for cellular homeostasis and survival. Main sources of intracellular NAD are the salvage pathways from nicotinamide, where Nicotinamide phosphoribosyltransferases (NAMPTs) and Nicotinamidases (PNCs) have a key role. NAMPTs and PNCs are important in aging, infection and disease conditions such as(More)