Luísa Castro

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—An agglomerative hierarchical clustering method, which uses both spectral and spatial information for the aggrega-tion decision, is proposed here. The method is suitable for large multispectral images, provided that an unsupervised classification is previously applied. The method is tested on a synthetic image and on a satellite image of the coastal zone.
MOTIVATION Ebola virus causes high mortality hemorrhagic fevers, with more than 25 000 cases and 10 000 deaths in the current outbreak. Only experimental therapies are available, thus, novel diagnosis tools and druggable targets are needed. RESULTS Analysis of Ebola virus genomes from the current outbreak reveals the presence of short DNA sequences that(More)
Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate phosphoribosyltransferase domain containing 1 (NAPRT1) are the main human NAD salvage enzymes. NAD regulates energy metabolism and cell signaling, and the enzymes that control NAD availability are linked to pathologies such as cancer and neurodegeneration. Here, we have screened normal and tumor(More)
Grid cells (GCs) in the medial entorhinal cortex (mEC) have the property of having their firing activity spatially tuned to a regular triangular lattice. Several theoretical models for grid field formation have been proposed, but most assume that place cells (PCs) are a product of the grid cell system. There is, however, an alternative possibility that is(More)
Grid cells in the medial entorhinal cortex (mEC) encode space in a particular way: their firing rate intensity forms an equilateral triangular lattice as the animal moves in the environment [1]. Models addressing the generation of grid fields fall into two major classes, both with important limitations [2]. Most models based on interference of oscillations(More)
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