Lourdes K Ledesma

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X-Linked dystonia parkinsonism (XDP) is a rapidly progressive and disabling neurodegenerative disease affecting mainly male Filipinos with origins from Panay Island. We reviewed all the past neurosurgical ablative procedures done for XDP patients listed in the Philippine XDP registry. From 1960 to 1982, six patients had undergone bilateral(More)
The natural history of sex-linked dystonia parkinsonism (XDP) has been well documented. However, its nonmotor features have not yet been fully described. We reviewed the available literature on the nonmotor features in XDP. We found five articles involving 79 XDP patients, three of which were on cognition and two on mood (anxiety and depression). There were(More)
Background and Objective: Patients who are afflicted with epilepsy are at an increase risk of developing anxiety and depression due to the uncertainties that they experience coupled with the low esteem and stigma attached to having epilepsy. Taylor 1 reported that seizure was significantly associated with anxiety, depression and stigma (P<0.0001 for all(More)
In summary then, the neuropsychological profile of Filipino parkinsonians reveals deficits in visuospatial processing, social judgment, attention and mental tracking, recent memory and word retrieval, aside from predicted difficulty in fine motor activities which would result in a deterioration of their penmanship. The frequency of dementia with this sample(More)
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