Louise Honeyman

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Atrial septal defect is one of the most common forms of congenital heart malformation. We identified a new locus linked with atrial septal defect on chromosome 14q12 in a large family with dominantly inherited atrial septal defect. The underlying mutation is a missense substitution, I820N, in α-myosin heavy chain (MYH6), a structural protein expressed at(More)
OBJECTIVES To test the hypothesis that a significant cause of rising medical admissions over the Christmas and New Year period is the failure of social and medical systems which support patients at home for most of the year; and to understand the reasons for admission during the winter months of an at risk population and to identify possible avoidable(More)
In New Zealand, the effect of resource constraint operates at two levels. In the macrocosm of national politics, there is a tectonic collision between two plates--social equity and a fiscal constraint on government expenditure. In the hospital, these forces are reflected in the frustration of the staff who cannot deliver that which they are trained to(More)
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