Louise Gagnon

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This study examines the specificity of the contribution of the right hemisphere to the processing of metaphoric meaning of words. Ten right- and 10 left-hemisphere-damaged subjects, and 20 normal control subjects were submitted to: (1) a word-triad task where they had to associate alternative metaphoric and non-metaphoric words to a target word, and to (2)(More)
The possible use of a calendar algorithm was assessed in DBC, an autistic "savant" of normal measured intelligence. Testing of all the dates in a year revealed a random distribution of errors. Re-testing DBC on the same dates one year later shows that his errors were not stable across time. Finally, DBC was able to answer "reversed" questions that cannot be(More)
This study examined the hypothesis of superior quantification abilities of persons with high functioning autism (HFA). Fourteen HFA individuals (mean age: 15 years) individually matched with 14 typically developing (TD) participants (gender, chronological age, full-scale IQ) were asked to quantify as accurately and quickly as possible numerosities,(More)
The intracarotid amobarbital test (IAT) is the most widely used procedure for pre-surgical evaluation of language lateralization in epileptic patients. However, apart from being invasive, this technique is not applicable in young children or patients who present mental retardation and/or language deficits. Functional magnetic resonance imaging (fMRI) is(More)
Anecdotal reports of superior estimation abilities in autistic individuals (e.g., Sacks, 1985) have never been confirmed empirically. We present here case studies of 2 children with autistic spectrum diagnoses and report remarkable abilities in estimation for several quantifiable dimensions. K.T. and G.T. were tested at 9 years of age for estimation of(More)
Unilateral hippocampal atrophy (HA) is considered as a precursor of mesial temporal sclerosis (MTS) in some patients with temporal lobe epilepsy. However, in other cases, it has been suggested that HA without MTS may constitute a distinct epileptic entity. Hippocampal atrophy without MTS was defined as HA without T2-weighted hyperintensity, loss of internal(More)
CACNA1A loss-of-function mutations classically present as episodic ataxia type 2 (EA2), with brief episodes of ataxia and nystagmus, or with progressive spinocerebellar ataxia (SCA6). A minority of patients carrying CACNA1A mutations develops epilepsy. Non-motor symptoms associated with these mutations are often overlooked. In this study, we report 16(More)