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  • Louis T. Curtis, Christopher G. England, Min Wu, John Lowengrub, Hermann B. Frieboes
  • Materials Science, Medicine
  • Nanomedicine
  • 2016 (First Published: 1 February 2016)
  • AIM Clinical translation of cancer nanotherapy has largely failed due to the infeasibility of optimizing the complex interaction of nano/drug/tumor/patient parameters. We develop an interdisciplinaryContinue Reading
  • Louis T. Curtis, Piotr G. Rychahou, Younsoo Bae, Hermann B. Frieboes
  • Chemistry, Medicine
  • Pharmaceutical Research
  • 2016 (First Published: 1 October 2016)
  • PurposePolymer nanoassemblies (PNAs) with drug release fine-tuned to occur in acidic tumor regions (pH < 7) while sparing normal tissues (pH = 7.4) were previously shown to hold promise asContinue Reading
  • Derek Reichel, Louis T. Curtis, +4 authors Younsoo Bae
  • Medicine, Chemistry
  • Pharmaceutical Research
  • 2017 (First Published: 1 November 2017)
  • PurposeTo develop polymer nanoassemblies (PNAs) modified with halofluorochromic dyes to allow for the detection of liver metastatic colorectal cancer (CRC) to improve therapeutic outcomes.MethodsWeContinue Reading