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Journals and Conferences
BACKGROUND & AIMS The aim of this study was to compare response to inactivated influenza vaccine in healthy children and pediatric patients with inflammatory bowel disease (IBD). METHODS A… (More)
This corrects the article DOI: 10.1038/nature23874
OBJECTIVES The role of infliximab in treating pediatric ulcerative colitis (UC) is not defined. The authors previously have described their experience with the open label use of infliximab in nine… (More)
The trillions of bacteria that make up the human microbiome are believed to encode functions that are important to human health; however, little is known about the specific effectors that commensal… (More)
Here we present a natural product discovery approach, whereby structures are bioinformatically predicted from primary sequence and produced by chemical synthesis (synthetic-bioinformatic natural… (More)
Bacterial culture broth extracts have been the starting point for the development of numerous therapeutics. However, only a small fraction of bacterial biosynthetic diversity is accessible using this… (More)
Viruses present in the human microbiome produce peptides homologous to human insulin/insulin-like growth factors that may influence host metabolic pathways.
Intermittent fasting helps to reduce diabetes-associated retinopathy through changes in microbiome bile acid metabolism.
Commensal bacteria are believed to have important roles in human health. The mechanisms by which they affect mammalian physiology remain poorly understood, but bacterial metabolites are likely to be… (More)
The forces that shape human microbial ecology are complex. It is likely that human microbiota, similarly to other microbiomes, use antibiotics as one way to establish an ecological niche. In this… (More)