Lorraine Sassano

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INTRODUCTION cognitive deterioration and reductions of bone health coincide with increasing age. We examine the relationship between bone composition and plasma markers of bone remodelling with measures of cognitive performance in healthy adults. METHODS this cross-sectional study included 225 old (52% women, mean age: 74.4 ± 3.3 years) and 134 young (52%(More)
Bone mineral density declines with increasing older age. We examined the levels of circulating factors known to regulate bone metabolism in healthy young and older adults. The circulating levels of dickkopf-1, osteocalcin, osteoprotegerin and sclerostin were positively associated with whole-body bone mineral density (WBMD) in older adults, despite the(More)
The purpose of our study was to verify the possibility of obtaining a reduction in the erythrocyte filtration rate and an improvement in the O2 tissue uptake in twenty patients suffering from insulin-dependent diabetes mellitus and diabetic angiopathy, randomly divided in two groups receiving pentoxifylline (1,200 mg/day for 30 days) or a placebo solution,(More)
The authors report their study on the red blood cell deformability of 30 patients with isolated and combined obstructive lesions in both aorto-iliac and femoral trunk, performed before and after the exercise test. Such a test does not significantly change the deformability in normal patients while, on the contrary, the exercise test significantly changes(More)
Hemorheological changes were more recently believed to be responsible for the pathogenesis of the Raynaud's phenomenon. In order to verify such changes, the authors report the data on red blood cell deformability obtained from a study performed in 8 patients with cold-induced Raynaud's phenomenon. From the evaluation of these data it seems likely that(More)
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