Lorna Stimson

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Chronic myeloid leukaemia is typically characterised by the presence of dysregulated BCR-ABL tyrosine kinase activity, which is central to the oncogenic feature of being resistant to a wide range of cytotoxic agents. We have investigated whether the inhibition of this tyrosine kinase by the novel compound STI571 (formerly CGP57148B) would render K562, KU812(More)
AHM23-24-Cover.indd 2 6/14/11 2:25:07 PM We are delighted to present the second Advanced Healthcare Materials special section in Advanced Materials. The fi rst section appeared in Issue 12 in March and was met with overwhelming praise by members of the community. We thank everyone who wrote to us directly, but also thank our authors, referees, and readers(More)