Lorie Fischer

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OBJECTIVE Individuals with anorexia nervosa are known to be ascetic and able to sustain self-denial of food as well as most comforts and pleasures in life. Building on previous findings of altered striatal dopamine binding in anorexia nervosa, the authors sought to assess the response of the anterior ventral striatum to reward and loss in this disorder. (More)
A random sample of 1,350 persons aged 65 years and older in a rural community underwent cognitive screening as part of a survey to establish a population-based registry of dementing disorders. The screening battery included the neuropsychological tests of the assessment protocol used in the National Institute on Aging multicenter Consortium to Establish a(More)
Anorexia nervosa (AN) is an illness characterized by aversion to ingestion of normally palatable foods. We examined whether there is a primary disturbance of taste processing and experience of pleasure using a sucrose/water task in conjunction with functional magnetic resonance imaging (fMRI). To avoid confounding effects of illness, 16 women recovered from(More)
Recent studies show that specific regions of the cortex contribute to modulation of appetitive behaviors. The purpose of this study was to determine whether neural response in these regions changes over time when a taste stimulus is administered repeatedly. Such a paradigm may be useful for determining whether altered habituation contributes to disturbed(More)
This paper reports on a comparison of the two alternative tests of attention in the Mini-Mental State Examination (MMSE), a well-known cognitive screening tool. The two tests, serial subtraction by seven and backwards spelling of the word world, are often used interchangeably. In a large population-based sample, the two tests were found to be weakly(More)
OBJECTIVE To describe the patterns of use of health and human services by elderly rural individuals and to determine whether cognitively impaired persons had a distinctive pattern of service utilization. DESIGN An epidemiological survey and cognitive screening of an age-stratified random community sample. SETTING The mid-Monongahela Valley, a rural(More)
OBJECTIVE It is possible that disturbances of systems modulating reward may contribute to a vulnerability to develop an eating disorder. METHOD This hypothesis was tested by assessing functional magnetic resonance brain imaging response to a monetary reward task known to activate the anterior ventral striatum (AVS), a region implicated in motivational(More)
Although psychiatric aftercare has received increased attention, little is known about patients' needs for community resources or about predischarge referral patterns. The authors interviewed hospital staff about needs and referrals for each of 747 patients about to be discharged. Nearly all patients had needs in the medical/therapeutic area and most(More)
Empirical tests of the reliability and validity of the Abel Assessment for Interest in Paraphilias (AAIP) as used with juvenile sexual offenders were performed. Test-retest reliability, screening validity, and diagnostic validity were assessed using several analytical approaches. The temporal stability, sensitivity, and specificity of the AAIP as used with(More)
Caregivers (n = 53) of patients with mild to moderate dementia administered a modified version of a cognitive examination at home to their patients. Comparisons between caregiver-administered examinations and the associated clinical examinations revealed a high degree of interrater reliability that was not affected by age or level of education of the(More)