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Early life dynamics of the human gut virome and bacterial microbiome in infants
The gut virome and bacterial microbiome were more similar between co-twins than between unrelated infants and the infant microbiome is highly dynamic and associated with early life changes in the composition of bacteria, viruses and bacteriophages with age.
Human stool contains a previously unrecognized diversity of novel astroviruses
This study used consensus astrovirus primers targeting the RNA polymerase to define the diversity of astroviruses present in pediatric patients with diarrhea on two continents, finding five samples contained sequences that were highly divergent from all previously described astrovIRuses.
Klassevirus 1, a previously undescribed member of the family Picornaviridae, is globally widespread
Klassevirus 1 is a previously undescribed picornavirus that is globally widespread and present on at least three continents that is highly divergent from, but most closely related to, members of the genus Kobuvirus.
Detection of newly described astrovirus MLB1 in stool samples from children.
- Stacy R. Finkbeiner, Binh-minh Le, Lori R. Holtz, G. Storch, David Wang
- Medicine, BiologyEmerging infectious diseases
- 1 March 2009
The prevalence of the recently identified astrovirus MLB1 in a cohort of children with diarrhea in St. Louis, Missouri, USA, was defined by reverse transcription-PCR and shows that astrov virus MLB1 is circulating in North America.
Human Polyomaviruses in Children Undergoing Transplantation, United States, 2008–2010
Samples from a longitudinal cohort were collected and the prevalence of polyomaviruses in children undergoing transplantation was defined, finding several were present in previously unreported specimen types.
Comparison of novel MLB-clade, VA-clade and classic human astroviruses highlights constrained evolution of the classic human astrovirus nonstructural genes.
Identification of a novel picornavirus related to cosaviruses in a child with acute diarrhea
It is proposed that this virus represents a new species in the Cosav virus genus, and it has tentatively been named Human Cosavirus E1 (HCoSV-E1), which appears to belong to the newly proposed picornavirus genus, Cosvirus.
Prevalence of classic, MLB-clade and VA-clade Astroviruses in Kenya and The Gambia
The most recently discoveredAstrovirus, MLB3, was the most prevalent and was found more commonly in control stools in The Gambia, while astrovirus MLB1 was associated with diarrhea in Kenya, and 3 unanticipated avian or canine astroviruses in the human stool samples were noted.
Detection of Novel Sequences Related to African Swine Fever Virus in Human Serum and Sewage
The discovery of novel viral sequences in human serum and sewage which are clearly related to the asfarvirus family but highly divergent from ASFV suggests that greater genetic diversity may exist among asfarviruses than previously thought and raises the possibility that human infection by asFarviruses may occur.
Propagation of Astrovirus VA1, a Neurotropic Human Astrovirus, in Cell Culture
The first cell culture system for VA1 is described, a key step necessary for the study of its ability to cause disease and the ability to propagate VA1 in cell culture will facilitate studies of the neurotropism and neuropathogenesis of VA1.