Lori Bukowski

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Perceptual comparison was investigated by gradually varying the relative length of two apparent motion paths, and independently determining when an initial percept was lost during the course of attribute change and when an alternative percept emerged. Dynamical comparison was indicated by a range of attribute values for which perception was bistable. Within(More)
2-Hydroxymethyl-1-methyl-1H-imidazo[4,5-b]pyridine was obtained and its oxidation was carried out. 1-Methyl-1H-2-imidazo[4,5-b]pyridinecarboxylic acid, its methyl ester, amide, nitrile, thioamide, amidoxime, hydrazide and hydrazidehydrazones were synthesized. Willgerodt-Kindler reaction of 1,2-dimethyl-1H-imidazo[4,5-b]pyridine was investigated. Some of the(More)
2-Acetylimidazo[4,5-b]pyridine was prepared and its reactions with some aromatic amines and sulfur (Willgerodt-Kindler reaction), some aromatic aldehydes, some carboxylic acid hydrazides as well as thiourea were investigated. New imidazo[4,5-b]pyridine derivatives with different substituents in 2-position (N-arylthioamides, imines, alpha, beta-unsaturated(More)
Based on the analysis of Quantitative Structure--Activity Relationships (QSAR) three representatives of imidazo[4,5-b]pyridine derivatives of predicted high antibacterial activity against Mycobacterium tuberculosis were synthetized and tested bacteriologically. Excellent agreement of the predicted and experimentally observed bioactivity was noted.(More)
Some reactions of 2-cyanomethyl-3-methyl-3H-imidazo[4,5-b]pyridine with isothiocyanates were carried out. New derivatives of imidazo[4,5-b]pyridine with different substituents in 2-position and derivatives of the new pyrido-imidazo-thiazine ring system were synthesized. Most of the obtained compounds were tested for their in vitro antituberculotic activity.
New derivatives of imidazo[4,5-b]pyridine and 9H-dipyrido-[1,2-a:3',2'-d]imidazole were synthesized. Antibacterial activity against Mycobacterium tuberculosis of selected compounds was determined. These data were combined with the corresponding bioactivity data previously generated for two other series of imidazo[4,5-b]pyridines. Analysis of Quantitative(More)
The reactions of corresponding 2,3-diamino-pyridines with succinic anhydride were carried out. 3-(2-Imidazo[4,5-b]pyridine)propionic acid and its N-1 and N-3 methyl derivatives were isolated. The acids obtained were converted into the esters, amides, nitriles, thioamides, amidoximes and hydrazides. Some of the synthesized compounds were tested for(More)