Lorena G Villagra

  • Citations Per Year
Learn More
Pregnancy increases body blood volume and cardiac output. These changes can exacerbate mitral stenosis symptoms. Symptomatic mitral stenosis during pregnancy has been successfully treated with percutaneous mitral valvuloplasty (PMV). We present the case of a 35-year-old white female who developed cardiogenic shock due to severe mitral stenosis at the 22nd(More)
OBJECTIVE To report our experience in patients with critical limb ischemia (CLI) due to isolated below-the-knee (BTK) arterial lesions. METHODS Between 1992 and 2009, we performed 2747 peripheral angioplasties, while 2.8% (78 of 2747) were only BTK and were included in the present study. RESULTS Mean age was 70.2 ± 11 years, 58.4% had diabetic, 85.7%(More)
A major limitation of cancer chemotherapy is development of resistance. In this study, we analyzed KB-3-1 cells and adriamycin-selected multidrug resistant sublines KB-A1 and KB-A10 cells for mechanisms of resistance. KB-A10 cells are 10-fold more resistant than KB-A1 cells but have lower P-glycoprotein. Of the known mechanisms of multidrug resistance,(More)
  • 1