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Methotrexate (MTX) is the disease modifying antirheumatic drug (DMARD) most commonly used in the treatment of rheumatoid arthritis (RA). It is recommended as first-line DMARD by the European League against Rheumatism (EULAR) and the American College of Rheumatology (ACR), alone or in combination with other DMARDs and biological agents. The most common side(More)
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