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  • Anne P. Beigneux, Brandon S J Davies, +17 authors Stephen G. Young
  • Biology, Medicine
  • Cell metabolism
  • 2007 (First Published: 1 April 2007)
  • The triglycerides in chylomicrons are hydrolyzed by lipoprotein lipase (LpL) along the luminal surface of the capillaries. However, the endothelial cell molecule that facilitates chylomicronContinue Reading
  • Shao H. Yang, Martin O. Bergo, +8 authors Loren G Fong
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2005 (First Published: 19 July 2005)
  • Hutchinson-Gilford progeria syndrome (HGPS), a progeroid syndrome in children, is caused by mutations in LMNA (the gene for prelamin A and lamin C) that result in the deletion of 50 aa withinContinue Reading
  • Catherine Coffinier, Sarah E Hudon, +4 authors Loren G Fong
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2007 (First Published: 14 August 2007)
  • HIV protease inhibitors (HIV-PIs) target the HIV aspartyl protease, which cleaves the HIV gag-pol polyprotein into shorter proteins required for the production of new virions. HIV-PIs are aContinue Reading