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Psychological quality of life (QOL), health-related QOL (HRQOL), and life satisfaction outcomes and their associated risk factors are reviewed for the large cohort of survivors and siblings in the Childhood Cancer Survivor Study (CCSS). This review includes previously published manuscripts that used CCSS data focused on psychological outcome measures,(More)
PURPOSE Psychological outcomes, health-related quality of life (HRQOL), and life satisfaction are compared between 7,147 adult childhood cancer survivors and 388 siblings from the Childhood Cancer Survivor Study, examining demographic and diagnosis/treatment outcome predictors. METHODS Psychological distress, HRQOL, and life satisfaction were measured by(More)
UNLABELLED The cold pressor task (CPT) involves placing a hand or forearm in cold water, a stimulus that produces a slowly mounting pain of mild to moderate intensity and is terminated by voluntary withdrawal of the limb. The CPT has been used in many studies of pain, autonomic reactivity, and hormonal stress responses. Use of the CPT with children was(More)
STUDY OBJECTIVE To examine the prevalence of and risk factors for fatigue and sleep disturbance among adult survivors of childhood cancer. DESIGN Retrospective cohort of childhood cancer survivors. SETTING Twenty-six academic institutions treating childhood cancer. PARTICIPANTS Two thousand six hundred forty-five survivors of childhood acute(More)
CONTEXT Yoga teachers and students often report that yoga has an uplifting effect on their moods, but scientific research on yoga and depression is limited. OBJECTIVE To examine the effects of a short-term Iyengar yoga course on mood in mildly depressed young adults. DESIGN Young adults pre-screened for mild levels of depression were randomly assigned(More)
BACKGROUND The effects of cancer and its treatment on reproduction and fertility are well-documented, yet knowledge of the psychosocial and behavioral ramifications of these outcomes for young adult survivors of childhood cancer is limited. As a qualitative exploratory study, this work identifies concerns, attitudes, and behaviors that may be associated(More)
BACKGROUND Increased attention has been directed toward the long-term health outcomes of survivors of childhood cancer. To facilitate such research, a multi-institutional consortium established the Childhood Cancer Survivor Study (CCSS), a large, diverse, and well-characterized cohort of 5-year survivors of childhood and adolescent cancer. PROCEDURE(More)
Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and(More)
UNLABELLED Under the auspices of the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT), 26 professionals from academia, governmental agencies, and the pharmaceutical industry participated in a 2-stage Delphi poll and a consensus meeting that identified core outcome domains and measures that should be considered in clinical(More)
PURPOSE To evaluate and compare psychological outcomes in long-term survivors of pediatric brain cancer and siblings of childhood cancer survivors, and to identify significant correlates of psychological distress. METHODS One thousand one hundred one adult survivors of childhood brain cancer and 2,817 siblings completed a long-term follow-up questionnaire(More)