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We examined how much depth we perceive when viewing a depiction of a slanted plane in which binocular disparity and monocular perspective provide different slant information. We exposed observers to a grid stimulus in which the monocular--and binocular-specified grid orientations were varied independently across stimulus presentations. The grids were(More)
Particularly promising studies on visual awareness exploit a generally used perceptual bistability phenomenon, "binocular rivalry"--in which the two eyes' images alternately dominate--because it can dissociate the visual input from the perceptual output. To successfully study awareness, it is crucial to know the extent to which eye movements alter the(More)
Categorization of seen objects is often determined by the shapes of objects. However, shape is not exclusive to the visual modality: The haptic system also is expert at identifying shapes. Hence, an important question for understanding shape processing is whether humans store separate modality-dependent shape representations, or whether information is(More)
In case of delayed visual feedback during visuomotor tasks, like in some sluggish computer games, humans can modulate their behavior to compensate for the delay. However, opinions on the nature of this compensation diverge. Some studies suggest that humans adapt to feedback delays with lasting changes in motor behavior (aftereffects) and a recalibration of(More)
The perception of a bistable stimulus as one or the other interpretation can be biased by prior presentations of that stimulus. Such learning effects have been found to be long lasting even after small amounts of training. The effectiveness of training may be influenced by preexposure to the ambiguous stimulus. Here we investigate the role of preexposure(More)
Random errors are omnipresent in sensorimotor tasks due to perceptual and motor noise. The question is, are humans aware of their random errors on an instance-by-instance basis? The appealing answer would be 'no' because it seems intuitive that humans would otherwise immediately correct for the errors online, thereby increasing sensorimotor precision.(More)
Adaptation to specific visuomotor mappings becomes faster when switching back and forth between them. What is learned when repeatedly switching between the visuomotor mappings: the absolute mappings or the relative shift between the mappings? To test this, we trained participants in a rapid pointing task using a unique color cue as context for each mapping(More)
The relationship between cellular metabolism and the cell cycle machinery is by no means unidirectional. The ability of a cell to enter the cell cycle critically depends on the availability of metabolites. Conversely, the cell cycle machinery commits to regulating metabolic networks in order to support cell survival and proliferation. In this review, we(More)
We experience the world mostly in a multisensory fashion using a combination of all of our senses. Depending on the modality we can select different exploration strategies for extracting perceptual information. For instance, using touch we can enclose an object in our hand to explore parts of the object in parallel. Alternatively, we can trace the object(More)
To investigate the underlying causes of chemoresistance in malignant pleural mesothelioma, we have studied mesothelioma cell lines as 3D spheroids, which acquire increased chemoresistance compared to 2D monolayers. We asked whether the gene expression of 3D spheroids would reveal mechanisms of resistance. To address this, we measured gene expression of(More)