Learn More
REASONS FOR PERFORMING STUDY Although beach training is commonly used in horses, limb loading on beach sand has never been investigated. A dynamometric horseshoe (DHS) is well adapted for this purpose. OBJECTIVES To compare ground reaction force (GRF) and fetlock kinematics measured in harness trotters on 2 tracks of beach sand with different water(More)
REASONS FOR PERFORMING STUDY The relationship between track surface properties and limb kinematics is poorly understood. Hoof orientation within the track surface has never been quantified under training conditions. Previously described kinematic and dynamic differences between leading and trailing forelimbs at the canter poorly correlate with(More)
Longitudinal sliding of horse's hooves at the beginning of stance can affect both performance and orthopaedic health. The objective of this study was to compare two measurement methods for quantifying hoof slip distances at training trot. The right front hoof of four French Trotters was equipped with an accelerometer (10 kHz) and kinematic markers. A firm(More)
The fungal cell wall is a dynamic structure that protects the cell from different environmental stresses suggesting that wall synthesizing enzymes are of great importance for fungal virulence. Previously, we reported the isolation and characterization of a mutant in class III chitin synthase, Bcchs3a, in the phytopathogenic fungus Botrytis cinerea. We(More)
OBJECTIVE With the current increase in sexually transmitted infections in industrialized countries, we assessed the characteristics and plasma viral load of HIV-1-infected patients reporting sexual behaviour at risk for HIV transmission (SBR). DESIGN The study population consisted of 223 patients with primary HIV-1 infection who were enrolled in the(More)
OBJECTIVES To assess the influence of patient characteristics, treatment precocity (how early) and duration of sustained virological response to highly active antiretroviral therapy (HAART) on HIV RNA levels after withdrawal of treatment started during primary infection and to compare HIV RNA levels after HAART withdrawal with levels reached at the same(More)
In the translational process of developing innovative therapies for DMD (Duchenne muscular dystrophy), the last preclinical validation step is often carried out in the most relevant animal model of this human disease, namely the GRMD (Golden Retriever muscular dystrophy) dog. The disease in GRMD dogs mimics human DMD in many aspects, including the(More)
OBJECTIVE To modelize the rate of CD4 cell count decline and its determinants after cessation of combination antiretroviral therapy (cART) started during primary HIV infection (PHI) and compare it with never-treated patients. METHODS Kinetics of CD4 counts were analyzed on the square root scale by using a mixed-effects model in 170 patients who received(More)
In survival analysis, exposure that appears or changes during the follow-up of subjects must be taken into account as a time-dependent covariate in the Cox proportional hazards model. Two types of time-dependent covariates are defined: covariates with unique change, and covariates with multiple changes. The way of taking into account such changes in the(More)
The relative efficacy of a collar containing 10% imidacloprid and 4.5% flumethrin (Seresto®, Bayer HealthCare Animal Health) and a spot on formulation containing 10% imidacloprid and 2.5% moxidectin (Advocate®, Bayer HealthCare Animal Health) was evaluated as a control measure to prevent canine thelaziosis in dogs in an endemic area of France. Ninety-six(More)