Lloyd H. Semprevivo

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A series ofH-2 and non-H-2 congenic resistant (CR) strains on a C57BL/10Sn background were infected with 107 amastigotes ofLeishmania donovani. Non-H-2 congenic strains B10.LP-H-3 b and B10.CE(30NX) and (B10.LP-H-3 b × B10)F1 hybrids showed a very rapid decrease in liver-parasite burdens beyond day 21. Parasite counts for these strains at day 35 were(More)
Nineteen congenic, resistant strains of mice on C57BL/10ScSn genetic background were infected with Leishmania donovani and the course of infection quantitated. Early in the infection, parasite burdens in the liver were similar for all strains, indicating that the parasite was able to establish, grow, and reproduce in the liver macrophages of each strain(More)
Lipids were extracted from adultOnchocerca gibsoni with chloroform/methanol and the total lipid content was characterized. Glycolipids were isolated from other lipid classes by Florisil column chromatography and were then fractionated by DEAE-Sephadex ionexchange chromatography. HPTLC revealed the presence of 9 neutral glycolipid bands and of 15 acidic(More)
A new procedure is described which enables gram quantities of adult Onchocerca tissue to be isolated from frozen connective tissue nodules, thus minimizing the risk of enzymatic degradation. Bovine connective tissue nodules containing adult Onchocerca gibsoni worms were obtained from Australia frozen at -70 degrees C and sectioned while still frozen into 3(More)
Effect of concomitant malaria on cutaneous leishmaniasis. Development of lesions in a Leishmania-susceptible (BALB/c) strain of mouse. Experimental Parasitology 65, 269-276. Symptoms of human leishmaniasis vary greatly, ranging from cryptic infections to cases with fatal sequelae. Factors regulating the severity of the disease are largely undetermined.(More)
We examined the effect of concurrent infection with Plasmodium yoelii and Leishmania mexicana amazonensis on the course of each disease in leishmania resistant C57Bl/6 mice. P. yoelii parasitemia was greatly enhanced when L. m. amazonensis was inoculated 2 days, 3 weeks, or 12 weeks prior to the malaria. Lesions due to L. m. amazonensis were enhanced in(More)