Lloyd D. Felton

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FROM THE STUDY OF DIFFERENT TISSUE EXTRACTS AS MEDIA FOR THE GROWTH OF PNEUMOCOCCI USED IN AN AUTOMATIC TRANSFER DEVICE, CERTAIN INFERENCES ARE WARRANTED: 1. Media made from calf lung or heart, or from horse skeletal muscle maintain virulence over a long period of time. Conversely, media made from calf spleen lead to a decrease in virulence. 2. Lung medium(More)
This paper is the second of a series on the study of virulence of microorganisms grown in vitro. Paper I t is a preliminary investigation and has to do with the influence of virulence on microorganisms transferred during the logarithmic increase phase-the period of optimum multiplication activity. In recent years, considerable attention has been directed(More)
It has been shown with one strain of pneumococcus (Type 1, Neufeld), that hydroquinine chloroacetanilide (C 29), hydroquinine p-chloroacetylaminophenol hydrochloride (C 36), hydroquinine m-chloroacetylaminophenol hydrochloride (C 40), and hyroquinine 4-chloroacetylaminopyrocathecol hydrochloride (C 110) have a rapid pneumococcidal activity both in vitro and(More)
1. An automatic apparatus is described by which a new supply of food can be furnished actively growing organisms at any desired interval of time-an automatic transferring device. 2. A single strain of pneumococcus, Type I, Neufeld, which had become avirulent for mice, acquired virulence of maximal degree when grown in the described apparatus with skimmed(More)
We are dealing, as the results show, with groups of chemicals, all of which, whether bacteriotropic or not, greatly inhibit the engulfing of Staphylococcus aureus by leucocytes. Not a sufficiently large number of experiments was performed in attempt to cure experimental staphylococcus infections to warrant any condusion in regard to possible therapeutic(More)
The growth of a virulent Type I pneumococcus in an automatic transfer device on a medium which aerobically maintains virulence results in a decrease in the presence of pure oxygen or pure carbon dioxide, but in no change in the presence of nitrogen. Whereas partial pressures of oxygen, that is 5 parts with 95 parts nitrogen by volume, and 10 parts with 90(More)