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This paper presents the design consideration of high order digital AZ modulators used as modulus controller for fractional-N frequency synthesizer. A third-order MASH structure (MASH 1-2) is designed and implemented which allows for the input to operate over 75% of the input adder capacity. The number of the output levels is reduced to two bits. The circuit(More)
BACKGROUND Optimizing treatment outcomes for depression requires understanding of how evidence-based treatments are utilized in clinical practice. Antipsychotic medications concurrent with antidepressant treatment are frequently used in major depression, but few studies have investigated trends and patterns of their use over time. This study aimed to(More)
This paper presents a general ring oscillator circuit to-pology for high speed operation, multiphase output and wide range tuning. The topology use sub-feedback inverters to construct fast loop for long chain ring oscillator to achieve high speed. The operating frequency of the ring oscillator is directly proportional to the transconductance (G,) of(More)
OBJECTIVE To evaluate the efficacy of Fluoro Jade-C staining (FJC) in the assessment of brain injury after deep hypothermia circulatory arrest (DHCA). METHODS Six healthy adult miniature male pigs underwent DHCA, the rectal temperature was down to 18°C, circulation was stopped , circulatory arrest was maintained for 60 minutes. On postoperative day 1,(More)
OBJECTIVE This study examined the use, demographic and clinical correlates of antipsychotic polypharmacy (APP) and its associations with treatment satisfaction and quality of life (QOL) in schizophrenia patients in China. METHOD A total of 4239 patients in 45 nationwide Chinese psychiatric hospitals/centers were interviewed in 2012 in the third(More)
Excessive activation of the transforming growth factor beta signaling pathway and disorganized cellular skeleton caused by genetic mutations are known to be responsible for the inherited thoracic aortic aneurysms and dissections (TAAD), a life-threatening vascular disease. To investigate the genotype–phenotype correlation, we screened genetic mutations of(More)
OBJECTIVE We examined the time trends and correlates of clozapine use in schizophrenia patients in China. METHOD A total of 14,013 patients with schizophrenia treated in 45 psychiatric hospitals/centers nationwide were interviewed in 2002, 2006 and 2012. Patients' socio-demographic and clinical characteristics including psychopathology, medication side(More)
Power supply for medical implantable devices (i.e. pacemaker) always challenges not only the surgery but also the battery technology. Here, we report a strategy for energy harvesting from the heart motion by using ultra-flexible piezoelectric device based on lead zirconate titanate (PZT) ceramics that has most excellent piezoelectricity in commercial(More)
OBJECTIVE Acute kidney injury (AKI) frequently occurs after catheter-based interventional procedures and increases mortality. However, the implications of AKI before thoracic endovascular aneurysm repair (TEVAR) of type B acute aortic dissection (AAD) remain unclear. This study evaluated the incidence, predictors, and in-hospital outcomes of AKI before(More)
Correspondence To the Editor: We report a strategy for an asymptomatic anastomotic pseudoaneurysm that occurred 30 years after aorta surgery. A 45-year-old male was admitted because the angiograph showed a pseudoaneurysm during an atrial fibrillation radiofrequency procedure. The patient did not have hypertension or chest pain. He had a history of thoracic(More)