Liz Milward

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The investigation of microarray expression data for large numbers of genes poses a number of challenges. Firstly, there is the challenge of transforming raw data to make it comparable across arrays and reduce technical variation while conserving true biological effects. Technical variation (eg cRNA loading, scanning and hybridisation inconsistency) can(More)
A blended approach encompassing problem-based learning (PBL) and structured inquiry was used in this laboratory exercise based on the congenital disease Osteogenesis imperfecta (OI), to introduce commonly used techniques in biomolecular analysis within a clinical context. During a series of PBL sessions students were presented with several scenarios(More)
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