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Hypothesis for potential pathogenesis of SARS-CoV-2 infection–a review of immune changes in patients with viral pneumonia
ABSTRACT Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with droplets and contact as the main means of… Expand
Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression.
The RASSF1A tumor suppressor gene is epigenetically silenced in a variety of cancers. Here, we perform a genome-wide human shRNA screen and find that epigenetic silencing of RASSF1A requires the… Expand
Biology and chemistry of Litsea cubeba, a promising industrial tree in China
Litsea cubeba (Lour.) Pers. (Lauraceae) is a promising industrial crop. The plant is rich in valuable essential oil, which is widely used as an ingredient in ionone flavors, botanical insecticides,… Expand
TGF‐α induces upregulation and nuclear translocation of Hes1 in glioma cell
Both the Notch‐signaling pathway and extracellular signal regulated kinase (ERK) cascade are involved in a wide variety of biological processes, such as proliferation, differentiation, survival, and… Expand
The impact of omega-3 fatty acid supplementation on glycemic control in patients with gestational diabetes: a systematic review and meta-analysis of randomized controlled studies
- L. Gao, Liyuan Lin, +4 authors L. Wang
- The journal of maternal-fetal & neonatal medicine…
- 1 May 2020
Abstract Background: Omega-3 fatty acid supplementation shows some treatment efficacy for gestational diabetes. This systematic review and meta-analysis is conducted to investigate the efficacy of… Expand
Detection of genetic diversity and selection at the coding region of the melanocortin receptor 1 (MC1R) gene in Tibetan pigs and Landrace pigs.
Domestication and subsequent selective pressures have produced a large variety of pig coat colors in different regions and breeds. The melanocortin 1 receptor (MC1R) gene plays a crucial role in… Expand
Purification, characterization and enzymatic synthesis of theaflavins of polyphenol oxidase isozymes from tea leaf (Camellia sinensis)
Abstract Polyphenol oxidase (PPO) plays a key role in tea processing, converting catechins into theaflavines. Two PPOs were isolated and purified from tea ( Camellia sinensis ) leaves. PPO1 and PPO2… Expand
Immune signature of T follicular helper cells predicts clinical prognostic and therapeutic impact in lung squamous cell carcinoma.
- F. Xu, Hongpan Zhang, Jiexin Chen, Liyuan Lin, Yongsong Chen
- International immunopharmacology
- 10 December 2019
Lung cancer is the leading reason of cancer-related death from cancer globally for both men and women. Recently, tumor immune heterogeneity has been implicated in cancer clinical outcome. However,… Expand
MiR-200b in heme oxygenase-1-modified bone marrow mesenchymal stem cell-derived exosomes alleviates inflammatory injury of intestinal epithelial cells by targeting high mobility group box 3
Heme Oxygen-1 (HO-1)-modified bone marrow mesenchymal stem cells (BMMSCs) are effective to protect and repair transplanted small bowel and intestinal epithelial cells (IECs); however, the mechanism… Expand
Microfilament regulatory protein MENA increases activity of RhoA and promotes metastasis of hepatocellular carcinoma.
- Liyuan Lin, X. Yang, J. Li, Y. Zhang, W. Qin, Z. Zhang
- Biology, Medicine
- Experimental cell research
- 10 September 2014
Mammalian enabled (MENA), usually known as a direct regulator of microfilament polymerization and bundling, promotes metastasis in various cancers. Here we focus on the role of MENA in hepatocellular… Expand