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Arachidonic acid (AA) is the major precursor of several classes of signal molecules and the alteration of its metabolism is involved in human carcinogenesis. For instance, 5-lipoxygenase (5-LOX) converts AA to hydroxyeicosatetraenoic acids or leukotrienes (LTs), which are able to enhance proliferation, increase survival and suppress the apoptosis of human(More)
—In this note, we will provide a new systematic approach to characterize and compute the stability bound of a singularly perturbed linear system. The approach is based on the feedback system representation of an additional matrix perturbation problem. The idea is to change the stability bound problem to the stability problem of an underlying feedback(More)
The problem of output feedback stabilization of linear systems based on a reduced-order model is addressed in this paper. New reduced-order models are proposed for the output feedback design of linear systems with a singular perturbation model. An output feedback controller with a zero steady-state gain matrix is proposed for stabilizing this kind of(More)
Being able to judge another person's visuo-spatial perspective is an essential social skill, hence we investigated the generalizability of the involved mechanisms across cultures and genders. Developmental, cross-species, and our own previous research suggest that two different forms of perspective taking can be distinguished, which are subserved by two(More)
'Sensory attenuation', i.e., reduced neural responses to self-induced compared to externally generated stimuli, is a well-established phenomenon. However, very few studies directly compared sensory attenuation with attention effect, which leads to increased neural responses. In this study, we brought sensory attenuation and attention together in a(More)
Sensory consequences resulting from own movements receive different neural processing compared to externally generated sensory consequences (e.g., by a computer), leading to sensory attenuation, i.e., a reduction in perceived intensity or brain evoked responses. However, discrepant findings exist from different cultural regions about whether sensory(More)