Arachidonic acid (AA) is the major precursor of several classes of signal molecules and the alteration of its metabolism is involved in human carcinogenesis. For instance, 5-lipoxygenase (5-LOX) converts AA to hydroxyeicosatetraenoic acids or leukotrienes (LTs), which are able to enhance proliferation, increase survival and suppress the apoptosis of human… (More)
—In this note, we will provide a new systematic approach to characterize and compute the stability bound of a singularly perturbed linear system. The approach is based on the feedback system representation of an additional matrix perturbation problem. The idea is to change the stability bound problem to the stability problem of an underlying feedback… (More)
The problem of output feedback stabilization of linear systems based on a reduced-order model is addressed in this paper. New reduced-order models are proposed for the output feedback design of linear systems with a singular perturbation model. An output feedback controller with a zero steady-state gain matrix is proposed for stabilizing this kind of… (More)
Being able to judge another person's visuo-spatial perspective is an essential social skill, hence we investigated the generalizability of the involved mechanisms across cultures and genders. Developmental, cross-species, and our own previous research suggest that two different forms of perspective taking can be distinguished, which are subserved by two… (More)
Infinite-impulse response (IIR) filters are one of the primary types of digital filters in digital signal processing (DSP) systems. Among many different IIR filters, a single-pole low-pass may be the most widely used filter in various applications.
Being able to predict self-generated sensory consequences is an important feature of normal brain functioning. In the auditory domain, self-generated sounds lead to smaller brain responses (e.g., auditory evoked responses) compared to externally generated sounds, which is usually referred to as the sensory attenuation effect. Here we investigated the role… (More)