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BACKGROUND Protease-activated receptors (PAR) are seven transmembrane G-coupled receptors comprising four genes (PAR-1 approximately PAR-4). Mast cell has been identified to be able to express PARs and release an array of cytokines upon activation. Recently, it was reported that interleukin (IL)-12 could regulate the expression of PARs in mast cells, and(More)
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