Lixia Fan

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The current study aims to optimize the compositions of platelet activation-inhibitors for a loading solution of lyophilizing protectants and to establish a series of perfect pretreatment methods for platelet lyophilization. The optimal combination of six kinds of inhibitors and loading solutions of lyophilizing protectants, including prostaglandin E1(More)
The incidence of rubella cases in China from 1991 to 2007 was reviewed, and the nucleotide sequences from 123 rubella viruses collected during 1999 to 2007 and 4 viral sequences previously reported from 1979 to 1984 were phylogenetically analyzed. Rubella vaccination was not included in national immunization programs in China before 2007. Changes in endemic(More)
Rubella remains a significant burden in mainland China. In this report, 667 viruses collected in 24 of 31 provinces of mainland China during 2010-2012 were sequenced and analyzed, significantly extending previous reports on limited numbers of viruses collected before 2010. Only viruses of genotypes 1E and 2B were found. Genotype 1E viruses were found in all(More)
The development of synthetic process for hollow silica materials is an issue of considerable topical interest. While a number of chemical routes are available and are extensively used, the diameter of hollow silica often large than 50 nm. Here, we report on a facial route to synthesis ultrafine hollow silica nanoparticles (the diameter of ca. 24 nm) with(More)
Previous work has shown that gap junction intercellular communication (GJIC) enhances cisplatin (Pt) toxicity in testicular tumor cells but decreases it in non-tumor testicular cells. In this study, these different GJIC-propagated effects were demonstrated in tumor versus non-tumor cells from other organ tissues (liver and lung). The downregulation of GJIC(More)
Three novel cyclic hexapeptides, designated NW-G05 (1), NW-G06 (2) and NW-G07 (3), were isolated from the fermentation broth of Streptomyces alboflavus 313. Their structures were elucidated on the basis of extensive spectroscopic analysis, MS experiments, and chemical analysis. Their antibacterial activities against several strains of bacteria were(More)
BACKGROUND AND OBJECTIVE It has been reported that 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH)-mediated photodynamic therapy (PDT) effects on antitumor. However, it remains unclear whether gap junction (GJ) acts on phototoxicity of HPPH and which pathways are involved in the process. MATERIALS AND METHODS We determine the effect of HPPH on(More)
S.M. Lee proposed the conjecture: for any n > 1 and any permutation f in S(n), the permutation graph P (P n , f) is graceful. For any integer n > 1 and permutation f in S(n), we discuss the gracefulness of the permutation graph P (P n , f) if f = l−1 k=0 (m + 2k, m + 2k + 1), and l−1 k=0 (m + 4k, m + 4k + 2)(m + 4k + 1, m + 4k + 3) for any positive integers(More)
We have designed and synthesized two porphyrin containing two-dimensional (2D) polymers based on the imine linkage. Both the 2D polymers are revealed to be 2D organic semiconductors with band gaps of around 1 eV. STM characterization reveals that the rigidity and affinity of building blocks to the surface has essential effects on the topology of the 2D(More)
Despite initially positive responses, recurrences after Photodynamic treatment (PDT) can occur and there is need for improvement in the effectiveness of PDT. Our study uniquely showed that there was a significantly gap junctional intercellular communication (GJIC)-dependent PDT cytotoxicity. The presence of GJIC composed of Connexin 32 increased the PDT(More)