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Ethanol extract of Schisandrae chinensis fructus ameliorates the extent of experimentally induced atherosclerosis in rats by increasing antioxidant capacity and improving endothelial dysfunction
TLDR
EESC positively affects the treatment of AS in vivo and the findings will provide a reliable theoretical basis for developing novel therapeutics. Expand
Serum Metabolic Profiling Reveals the Antidepressive Effects of the Total Iridoids of Valeriana jatamansi Jones on Chronic Unpredictable Mild Stress Mice
TLDR
It is confirmed that IRFV exerted an antidepressive effect by regulating multiple metabolic pathways, including the tricarboxylic acid cycle, the synthesis of neurotransmitters, and amino acid metabolism. Expand
Anti-invasion and anti-metastasis effects of Valjatrate E via reduction of matrix metalloproteinases expression and suppression of MAPK/ERK signaling pathway.
TLDR
Findings provide new evidence that mitogen-activated protein kinase/extracellular signal regulated kinase (MAPK/ERK) signaling pathway plays an important role in promoting invasion and metastasis in HepG2 cells through p-ERK, and MAPK/ ERK signaling pathway may be a therapeutic target for tumor. Expand
Antidepressant Effects and Mechanisms of the Total Iridoids of Valeriana jatamansi on the Brain-Gut Axis.
TLDR
The antidepressant effects of TIV may be related to gut flora structures and regulation of 5-HT, NE, SP, and CRF in the brain and intestine and the diversity and richness of gut microbes increased compared to the model group. Expand
Ameliorative effects of escin on neuropathic pain induced by chronic constriction injury of sciatic nerve.
TLDR
Elin exerted the ameliorative effects on NP induced by CCI which may be related to downregulating the release of pro-inflammatory cytokines, suppressing TLR-4/NF-κB signal pathway, thereafter decreasing the level of GFAP and NGF. Expand
Utilization of HMG-CoA reductase inhibitors in 71 primary medical institutions in Beijing from 2010 to 2012
TLDR
The most frequently used HMG-CoA reductase inhibitors were atorvastatin and simVastatin in primary medical institutions in Beijing and their consumption sum was about 90% of the total consumption sum. Expand
Summary of TCM Treatment of Anal Swelling
People have become more sensitive to the local discomfort of the anus in recent years as their quality of life has improved. Anal bulge, which is related to Chinese medicine’s “post-heavy,” is aExpand
U. diffracta extract mitigates high fat diet and VD3-induced atherosclerosis and biochemical changes in the serum liver and aorta of rats.
TLDR
The mechanism of the antiatherogenic effects of the ethanol extract of U. diffracta may be related to promoting the expression of serum IL-10 and inhibition of TLR5/NF-κB signaling pathway. Expand
The relationship between the consumption sum of five kinds of commonly used respiratory medicines and seasons
TLDR
The consumption sum of respiratory medicines is affected by seasons and is largest in winter and the turning period of seasons. Expand
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