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OBJECTIVE Shikonin possesses anti-inflammatory effects. However, its function in concanavalin A-induced acute liver injury remains uncertain. The aim of the present study was to investigate the functions of shikonin and its mechanism of protection on ConA-induced acute liver injury. MATERIALS AND METHODS Balb/C mice were exposed to ConA (20 mg/kg) via(More)
Glycolysis, as an altered cancer cell-intrinsic metabolism, is an essential hallmark of cancer. Phosphofructokinase (PFK) is a metabolic sensor in the glycolytic pathway, and restricting the substrate availability for this enzyme has been researched extensively as a target for chemotherapy. In the present study, we investigated that the effects of(More)
Aims. To investigate cerebral hemodynamics in cirrhotic patients with HE and to observe effects of treatment in cerebral hemodynamics and correlations among ammonia, cerebral hemodynamics, and cognitive function. Methods. There were four groups: healthy controls (group 1), cirrhosis without HE (group 2), cirrhosis with MHE (group 3), and cirrhosis with OHE(More)
A novel nano-stages system included wafer stage and reticle stage used for LED photolithography equipment with 0.8 micro technology node (half pitch) was proposed. A method of standstill dynamic error of synchronization control (SDSC) minimized the relative difference between motions of two stages. In order to improving the synchronization control error of(More)
An optimized structure of a voice coil motor with a lower force ripple was presented. Through improving the part of the magnet or the back iron of a voice coil motor's structure, its internal vertical peak flux density was reduced greatly. In this way, the motor's peak force was also reduced with force ripple. Different optimization results were compared(More)
Objective. The present study was conducted to compare the efficacy of metformin combined with diammonium glycyrrhizinate enteric-coated capsule (DGEC) versus metformin alone versus DGEC alone for the treatment of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM). Subjects and Methods. 163 patients with NAFLD and T2DM(More)