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Ochratoxin A Producing Fungi, Biosynthetic Pathway and Regulatory Mechanisms
This review focuses on three aspects of OTA: OTA-producing strains, OTA biosynthetic pathway and the regulation mechanisms of Ota production. Expand
Effects of Essential Oil Citral on the Growth, Mycotoxin Biosynthesis and Transcriptomic Profile of Alternaria alternata
Citral is indicated as a potential antifungal and antimytoxigenic alternative for cereal storage and the inhibitory effects of the essential oil citral on the fungal growth and mycotoxin production of A. alternata are evaluated. Expand
Fahr's disease in two siblings in a family: A case report.
Although the two patients had distinct clinical manifestations, they both had similar intracranial multiple calcifications and the computed tomography scan remains the main method used in the diagnosis of Fahr's disease. Expand
Oolong, black and pu-erh tea suppresses adiposity in mice via activation of AMP-activated protein kinase.
The results indicate that oolong, black and pu-erh tea, and in particular, black tea, suppresses adiposity via phosphorylation of the key metabolic regulator AMPK and increases browning of WAT. Expand
Procyanidin Promotes Translocation of Glucose Transporter 4 in Muscle of Mice through Activation of Insulin and AMPK Signaling Pathways
Procyanidins, especially cinnamtannin A2, one of the tetramers, was the most effective and significantly ameliorate postprandial hyperglycemia at least in part by promoting GLUT4 translocation to the plasma membrane by activating both insulin- and AMPK-signaling pathways. Expand
A Consensus Ochratoxin A Biosynthetic Pathway: Insights from the Genome Sequence of Aspergillus ochraceus and a Comparative Genomic Analysis
  • Yan Wang, Liuqing Wang, +8 authors Y. Liu
  • Medicine, Biology
  • Applied and Environmental Microbiology
  • 27 July 2018
A consensus OTA biosynthesis pathway exists in all OTA-producing fungi and is encoded by a gene cluster containing four highly conserved biosynthetic genes and a bZIP transcription factor and is demonstrated to be consensus. Expand
An analysis method for flavan-3-ols using high performance liquid chromatography coupled with a fluorescence detector.
The developed method to measure procyanidins in black soybean seed coat extract (BE) prepared from soybeans grown under three different fertilization conditions, namely, conventional farming, basal manure application, and intertillage and indicated that up to the tetramer oligomerization, procyAnidins were detectable and flavan-3-ols mainly existed in conjugated forms in the plasma. Expand
Functional Characterization of New Polyketide Synthase Genes Involved in Ochratoxin A Biosynthesis in Aspergillus Ochraceus fc-1
This study suggests that AoOTApks-1 could be involved in OTA biosynthesis, while AoOT Apks-2 might be indirectly involved in ochratoxin A production. Expand
pH-Signaling Transcription Factor AopacC Regulates Ochratoxin A Biosynthesis in Aspergillus ochraceus.
  • Y. Wang, Fei Liu, +6 authors Y. Liu
  • Chemistry, Medicine
  • Journal of agricultural and food chemistry
  • 13 April 2018
It is suggested that AopacC is an alkaline-induced regulator responsible for growth and OTA biosynthesis in A. ochraceus and this regulatory mechanism might be pH-dependent. Expand
Absorption, metabolism, distribution and faecal excretion of B-type procyanidin oligomers in mice after a single oral administration of black soybean seed coat extract.
Monomeric unit (-)-epicatechin had the highest bioavailability, followed by procyanidin B2, procyansidin C1 and cinnamtannin A2, and their monomersic unit -)-epicateschin distributed widely, primarily in their free forms. Expand