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In cloud datacenters, effective resource provisioning is needed to maximize energy efficiency and utilization of cloud resources while guaranteeing the Service Level Agreement (SLA) for tenants. Previous resource provisioning strategies either allocate physical resources to virtual machines (VMs) based on static VM resource demands or dynamically handle the(More)
To provide robust infrastructure as a service (IaaS), clouds currently perform load balancing by migrating virtual machines (VMs) from heavily loaded physical machines (PMs) to lightly loaded PMs. The unique features of clouds pose formidable challenges to achieving effective and efficient load balancing. First, VMs in clouds use different resources (e.g.,(More)
In cloud datacenters, multiple Virtual Machines (VMs) are co-located in a Physical Machine (PM) to serve different applications. Prior VM consolidation methods for cloud datacenters schedule VMs mainly based on resource (CPU and memory) constraints in PMs but neglect serious shared Last Level cache contention between VMs. This may cause severe VM(More)
The fabrication of core-shell structural nanosilica@liposome nanocapsules as a drug delivery vehicle is reported. SiO(2) nanoparticles are encapsulated within liposomes by a W/O/W emulsion approach to form supramolecular assemblies with a core of colloidal particles enveloped by a lipid bilayer shell. A nanosilica core provides charge compensation and(More)
The interaction and association between chitosan and hemoglobin (Hb) are studied by UV-vis and fluorescence spectroscopies, viscometry, circular dichroism, dynamic and static light scattering. Chitosan can obviously associate with Hb to form protein-chitosan complexes, which affects microstructure of Hb. The distance between the first association site of(More)
To provide robust infrastructure as a service (IaaS), clouds currently perform load balancing by migrating virtual machines (VMs) from heavily loaded physical machines (PMs) to lightly loaded PMs. Previous reactive load balancing algorithms migrate VMs upon the occurrence of load imbalance, while previous proactive load balancing algorithms predict PM(More)
In cloud systems, achieving high resource utilization and low Service Level Objective (SLO) violation rate are important to the cloud provider for high profit. For this purpose, recently, some methods have been proposed to predict allocated but unused resources and reallocate them to long-running service jobs. However, the accuracy of their prediction(More)
Functioning as an intermediary between tenants and cloud providers, cloud service brokerages (CSBs) can bring about great benefits to the cloud market. CSBs buy the cloud resources, i.e., servers, with lower prices from cloud providers and sell the resources to the tenants with higher prices. To maximize its own profit, a CSB may distribute tenants'(More)
OBJECTIVE Alterations in microRNA (miRNA) expression have been described in thyroid tumors, suggesting a role for miRNAs in thyroid carcinogenesis. BRAF(V600E) is the most frequently identified genetic alteration in papillary thyroid carcinoma (PTC). We investigated the link between BRAF(V600E) status and the expression of miRNAs in PTC and analyzed the(More)
Cloud providers are charged by ISPs for inter-datacenter transfers under the dominant percentile-based charging models. In order to minimize the payment costs, existing works aim to keep the traffic on each link under the charging volume. However, these methods cannot fully utilize each link's available bandwidth capacity, and may increase the charging(More)