Liubov Barbinova

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The objective of this study was to investigate the clinical and diagnostic impact of baseline exhaled nitric oxide (eNO) levels and latex allergen-induced eNO changes in different healthcare worker groups. Healthcare workers, 31 latex-sensitised and 14 nonsensitised, underwent occupational-type challenge tests with powdered allergenic latex gloves.(More)
UNLABELLED The objective of this study was to evaluate the role of eNO changes post inhalative isocyanate challenge tests (DeltaeNO) with regard to specific asthmatic reactions and unspecific bronchial hyperresponsiveness (BHR) to predict clinical and subclinical responses of isocyanate workers. METHODS 55 workers with isocyanate-related respiratory(More)
OBJECTIVE Nitric oxide (NO) levels in the exhaled air of asthmatic patients have been shown to be increased. This observation has also been reported in workers who are allergic to laboratory animals. To determine if a challenge test with natural rubber latex (NRL) or 4,4'-diphenylmethane diisocyanate (MDI) would also produce an increase of NO exhalation in(More)
BACKGROUND We have investigated the relationship between atopic status and long-term occupational exposure to latex proteins or methyl diethyl diisocyanate (MDI) as high and low molecular weight asthma-inducing agents, respectively. METHODS This study is based on retrospective analyses of two groups of symptomatic outpatients: 184 healthcare workers with(More)
A clear diagnosis of occupational asthma in hairdressers usually is difficult since standardized tests are lacking. We investigated the potential role of F (E)NO measurements for complementary diagnostic and pathophysiological assertions. Only a few of the work-related respiratory complaints of fifteen examined hairdressers were associated with a(More)
Our aim was to determine by means of five exhaled flow rates differential parameters of FeNO and the relations between them in smokers and non-smokers. 34 smokers (without respiratory symptoms and medication) were examined. Compared to 43 healthy non-smokers, FeNO was significantly lower. The analysis of the differential NO parameters by means of the(More)
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