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OBJECTIVES To examine the association between maternal prepregnancy weight and child neurodevelopment, and the effect of gestational weight gain. METHODS Using the U.S. Collaborative Perinatal Project data, 1959-76, a total of 30,212 women with a calculable prepregnancy body mass index (BMI) and gestational weight gain, and term singleton children(More)
OBJECTIVE To estimate gestational age-specific risks of fetal death in pregnancies complicated by preeclampsia. METHODS Population-based cohort study comprising all singleton births (N=554,333) without preexisting chronic hypertension recorded in the Norwegian Medical Birth Registry from 1999 to 2008. Additional data come from a subset of preeclamptic(More)
INTRODUCTION Prepregnancy obesity is associated with increased morbidity and mortality for mother and offspring. The objective of our study is to estimate the effect of maternal prepregnancy weight on placental pathological lesions.. METHODS Data used for this study were from the U.S. Collaborative Perinatal Project, a large prospective cohort study. It(More)
UNLABELLED Abstract Background: Recent meta-analyses indicate that children delivered by cesarean section have increased risk for asthma. However, the studies included in these previous meta-analyses showed significant heterogeneity. Furthermore, no previous meta-analysis has distinguished the association of elective and emergency CS, spontaneous and(More)
With the increasing recognition of the importance of the non-skeletal effects of vitamin D (VitD), more and more attention has been drawn to VitD status in early life. However, the VitD status of newborns and factors that influence VitD levels in Shanghai, China, remain unclear. A total of 1030 pregnant women were selected from two hospitals in Shanghai,(More)
Wilson disease is an inherited autosomal recessive disorder causing copper accumulation and consequent toxicity. d-Penicillamine, a potent metal chelator, is an important therapy for Wilson disease. To investigate the changes of metal elements under the treatment of d-penicillamine, we determined the levels of Cu, Zn, Mg, Ca, Fe, Se, Mn, Pb, Hg, Cd, As, Tl,(More)
BACKGROUND AND OBJECTIVES Image-assisted dietary assessment methods are frequently used to record individual eating habits. This study tested the validity of a smartphone-based photographic food recording approach by comparing the results obtained with those of a weighed food record. We also assessed the practicality of the method by using it to measure the(More)
OBJECTIVE This study aimed to investigate early predictors (6 months after diagnosis) of medical intractability in epilepsy. METHODS All children <12 years of age having two or more unprovoked seizures 24 h apart at Xinhua Hospital between 1992 and 2006 were included. Medical intractability was defined as failure, due to lack of seizure control, of more(More)
BACKGROUND Umbilical cord blood is an economical and easy to obtain source of high-quality neonatal genomic DNA. However, although large numbers of cord blood samples have been collected, information on the yield and quality of the DNA extracted from cord blood is scarce. Moreover, considerable doubt still exists on the utility of the buffy coat instead of(More)
Large-for-gestational-age (LGA) babies have a higher risk of metabolic disease later in life, and their postnatal growth in early childhood may be associated with long-term outcomes. This study is aimed to determine childhood health outcomes of term LGA babies with different growth patterns. Data were obtained from the U.S. Collaborative Perinatal Project(More)