Lishuang Zhang

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Eliciting a broadly neutralizing antibody response against the HIV-1 membrane-proximal external region (MPER) mimicking the activity of 4E10 and 2F5 monoclonal antibodies remains a major challenge. In this study, two novel tetra-branched peptide immunogens, 4E10- and 2F5-MAP4, were designed and synthesized using a MAP system. Guinea pigs were immunized with(More)
This paper deals with planning a trajectory from a start pose to a goal pose for an indoor mobile robot. The problem of trajectory planning is first separated into path planning and generation of translational velocity profile to execute the path. Path planning is further composed of generating waypoints and generating joint Bezier curve path connected by(More)
This paper proposes a method on path planning for mobile robots in the environment with some unknown obstacles. The whole planner consists of three parts. First, generate the global path from the given start pose to goal pose according to the known map of environment. Then when robot following the planned path, the module of threat assessment check whether(More)
Efficient gene transfer is a critical goal in retroviral transduction. Several peptides capable of forming amyloid fibrils, such as the 39-residue semen-derived infection-enhancing peptide (SEVI), have demonstrated the ability to boost retroviral gene delivery. Here, a 13-residue peptide P13 (Ac-(671) NWFDITNWLWYIK(683)) derived from the membrane-proximal(More)
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