Lisa Mcdermott

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BACKGROUND Studies examining the way in which cognitive impairment is associated with depression have produced inconsistent findings. Different severity of depressed mood across studies may account for such conflicting reports. However, inconsistent results have also been reported in relation to the specific association of depression severity with cognitive(More)
BACKGROUND Neuropsychological impairment is a key feature of late-life depression, with deficits observed across multiple domains. However, it is unclear whether deficits in multiple domains represent relatively independent processes with specific neural correlates or whether they can be explained by cognitive deficits in executive function or processing(More)
OBJECTIVE Postoperative mediastinitis after median sternotomy is associated with disability and mortality. The aim of this study was to identify risk factors for mortality 1 year after postoperative mediastinitis diagnosis. METHODS Postoperative mediastinitis was defined as an organ-space infection involving the mediastinum and necessitating debridement.(More)
BACKGROUND Cardiovascular risk factors and diseases are important etiological factors in depression, particularly late-life depression. Brain changes associated with vascular disease and depression can be detected using magnetic resonance imaging. Using diffusion tensor imaging (DTI), we investigated whether the Framingham Stroke Risk Profile (FSRP), a(More)
BACKGROUND Non-adherence to clinical guidelines has been identified as a consistent finding in general practice. The purpose of this study was to develop theory-informed, computer-delivered interventions to promote the implementation of guidelines in general practice. Specifically, our aim was to develop computer-delivered prompts to promote guideline(More)
OBJECTIVE To provide the first systematic in-depth description of the consequences of developmental prosopagnosia (DP; 'face blindness') for psychosocial functioning and occupational disability, in order to determine what kind of professional intervention may be needed. METHODS Semi-structured telephone interviews were carried out with 25 people whose(More)
BACKGROUND There is growing interest in conducting clinical and cluster randomized trials through electronic health records. This paper reports on the methodological issues identified during the implementation of two cluster randomized trials using the electronic health records of the Clinical Practice Research Datalink (CPRD). METHODS Two trials were(More)
OBJECTIVE To estimate the effectiveness of different strategies involving delayed antibiotic prescription for acute respiratory tract infections. DESIGN Open, pragmatic, parallel group, factorial, randomised controlled trial. SETTING Primary care in the United Kingdom. PATIENTS 889 patients aged 3 years and over with acute respiratory tract infection,(More)
OBJECTIVES Overutilisation of antibiotics may contribute to the emergence of antimicrobial drug resistance, a growing international concern. This study aimed to analyse the performance of UK general practices with respect to antibiotic prescribing for respiratory tract infections (RTIs) among young and middle-aged adults. SETTING Data are reported for 568(More)
BACKGROUND Patients frequently experience sleep problems and present to primary care. However, information is limited regarding the management strategies that GPs employ. AIM To gain an understanding of current GP management strategies for insomnia. DESIGN AND SETTING A postal questionnaire survey and qualitative interviews with GPs in the south of(More)