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  • Craig D. Fisher, Andrew J. Lickteig, +4 authors Nathan J Cherrington
  • Biology, Medicine
  • Drug Metabolism and Disposition
  • 2009 (First Publication: 1 October 2009)
  • Members of the cytochrome P450 (P450) enzyme families CYP1, CYP2, and CYP3 are responsible for the metabolism of approximately 75% of all clinically relevant drugs. With the increased prevalence ofExpand
  • Andrew J. Lickteig, Craig D. Fisher, +5 authors Nathan J Cherrington
  • Chemistry, Medicine
  • Drug Metabolism and Disposition
  • 2007 (First Publication: 1 October 2007)
  • Efflux transporters are responsible for the excretion of numerous xenobiotics and endobiotics and thus play an essential role in proper liver and kidney function. Nonalcoholic fatty liver diseasesExpand
  • Craig D. Fisher, Andrew J. Lickteig, +4 authors Nathan J Cherrington
  • Chemistry, Medicine
  • European journal of pharmacology
  • 2009 (First Publication: 1 June 2009)
  • Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of diagnoses ranging from simple fatty liver (SFL), to non-alcoholic steatohepatitis (NASH). This study aimed to determine the effectExpand
  • Craig D. Fisher, Lisa M. Augustine, +5 authors Nathan J Cherrington
  • Medicine, Chemistry
  • Drug Metabolism and Disposition
  • 2007 (First Publication: 1 June 2007)
  • Garlic oil (GO) contains several linear sulfur compounds, including diallyl sulfide (DAS), diallyl disulfide (DADS), and diallyl trisulfide (DATS), that induce drug-metabolizing enzymes such as CYP2BExpand
  • Andrew J. Lickteig, Xingguo Cheng, Lisa M. Augustine, Curtis D. Klaassen, Nathan J Cherrington
  • Biology, Medicine
  • Life sciences
  • 2008 (First Publication: 1 July 2008)
  • Transporters are expressed in a wide variety of tissues where they perform the critical function of enabling anionic and cationic chemicals of exogenous and endogenous origin to cross otherwiseExpand
  • Mary Beth Genter, Mansi Krishan, Lisa M. Augustine, Nathan J Cherrington
  • Medicine, Chemistry
  • Drug Metabolism and Disposition
  • 2010 (First Publication: 1 October 2010)
  • Uptake of drugs and other xenobiotics from the nasal cavity and into either the brain or systemic circulation can occur through several different mechanisms, including paracellular transport andExpand