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In 1994, IBM began to reengineer its global supply chain. It wanted to achieve quick responsiveness to customers with minimal inventory. To support this effort, we developed an extended-enterprise supply-chain analysis tool, the Asset Management Tool (AMT). AMT integrates graphical process modeling, analytical performance optimization, simulation,(More)
Patients with breast cancer (BC) undergoing neoadjuvant chemotherapy (NACT) may experience metastatic relapse despite achieving a pathologic complete response. We analyzed patients with BC before and after NACT for disseminated tumor cells (DTCs) in the bone marrow(BM); comprehensively characterized circulating tumor cells (CTCs), including stem cell–like(More)
Deep sedation is being provided at an increasing rate for patients undergoing bone marrow biopsy and aspiration (BMBA). The aim of this study was to establish the safety of deep sedation used for adults undergoing BMBA. A nonrandomized database analysis and retrospective review of patient records from January 1997 to December 2000 was performed; 5,811(More)
The HLA-G molecule belongs to the family of nonclassical human leukocyte antigen (HLA) class I. At variance to classical HLA class I, HLA-G displays (i) a low number of nucleotide variations within the coding region, (ii) a high structural diversity, (iii) a restricted peptide repertoire, (iv) a limited tissue distribution and (v) strong immune-suppressive(More)
A web-based training tool for interpreting dental radiographic images was developed at University of Wisconsin - Milwaukee (UWM) and evaluated at Marquette University (MU) dental school. The tool provides a self-instructional environment that will simulate the teacher- student interaction in the instruction of the interpretation of dental diagnostic images(More)
This article describes the benefits and dental applications of a three-dimensional imaging technique known as cone beam volumetric tomography (CBVT). When compared to conventional medical CT scanners, CBVT is more accurate, requires less radiation, captures the maxilla and mandible in a single rotation of the X-ray source, and is cost-effective for(More)
The non-classical human leukocyte antigen G (HLA-G) molecule and its soluble forms exert multiple immune suppressive regulatory functions in malignancy and in stem cells contributing to immune escape mechanisms. HLA-G can be secreted as free soluble HLA-G molecules or via extracellular vesicles (EVs). Here we evaluated these soluble HLA-G forms as(More)
OBJECTIVE To study the impact of parental leave on extending residency training and the timing of entrance into the specialty board certification examination system. METHODS From June 3, 2005, through December 28, 2005, primary specialty board policies regarding parental leave, absence from training, and the timing of entrance into the board certification(More)