Lisa J. McQuay

2Catherine B. Johannes
2Kenneth J. Rothman
2Daniel Fife
2Alejandro Arana
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Assigning biological functions to uncharacterized proteins is a fundamental problem in the postgenomic era. The increasing availability of large amounts of data on protein-protein interactions (PPIs) has led to the emergence of a considerable number of computational methods for determining protein function in the context of a network. These algorithms,(More)
We show here that the problem of maximizing a family of quantitative functions, encompassing both the modularity (Q-measure) and modularity density (D-measure), for community detection can be uniformly understood as a combinatoric optimization involving the trace of a matrix called modularity Laplacian. Instead of using traditional spectral relaxation, we(More)
STUDY OBJECTIVE To estimate the incidence and relative risk of a hospitalization or emergency visit for noninfectious liver injury in users of eight oral antimicrobials-amoxicillin, amoxicillin-clavulanic acid, clarithromycin, cefuroxime, doxycycline, levofloxacin, moxifloxacin, telithromycin-compared with nonusers of these antimicrobials. DESIGN(More)
  • Alejandro Arana, Catherine B. Johannes, Lisa J. McQuay, Cristina Varas-Lorenzo, Daniel Fife, Kenneth J. Rothman
  • 2015
INTRODUCTION Epidemiological studies have linked domperidone use with serious cardiac arrhythmias, including sudden cardiac death, but data on age, dose, and duration of use are limited. OBJECTIVES The aim of this study was to assess the risk of out-of-hospital sudden cardiac death associated with domperidone use versus proton pump inhibitors (PPIs),(More)
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