Lisa J Croucher

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OBJECTIVE To develop recommendations to enable successful inclusion of the patient perspective in European League Against Rheumatism (EULAR)-funded scientific research projects. METHODS The EULAR standardised operational procedures for guideline development were followed. A systematic literature review was presented during a first task force meeting,(More)
BACKGROUND A number of studies, notably EPIC, have shown a descrease in colorectal cancer risk associated with increased fibre consumption. Whilst the underlying mechanisms are likely to be multifactorial, production of the short-chain fatty-acid butyrate fro butyratye is frequently cited as a major potential contributor to the effect. Butyrate inhibits(More)
BACKGROUND Markers of crypt cell proliferation are frequently employed in studies of the impact of genetic and exogenous factors on human colonic physiology. Human studies often rely on the assessment of tissue acquired at endoscopy. Modulation of cell proliferation by bowel preparation with oral laxatives may confound the findings of such studies, but(More)
Aims—To investigate the relative stability of collagen metabolites in degrading cartilage. Methods—New antipeptide antibodies to denaturation epitopes located in the N-terminal and C-terminal regions of the type II collagen helix have been made and characterised. Type II collagen fragments in the conditioned medium from cultures of degrading bovine nasal(More)
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