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  • Philipp Emnet, Sally Gaw, Grant L. Northcott, Bryan C. Storey, Lisa Fletcher Graham
  • Chemistry, Medicine
  • Environmental research
  • 2015
  • Pharmaceutical and personal care products (PPCPs) are a major source of micropollutants to the aquatic environment. Despite intense research on the fate and effects of PPCPs in temperate climates,Continue Reading
  • Wenting Li, Kaliappanadar Nellaiappan, Timothy Strassmaier, Lisa Fletcher Graham, K M Thomas, Herbert M. Kagan
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1997 (First Publication: 25 November 1997)
  • Lysyl oxidase (EC 1.4.3.13) oxidizes peptidyl lysine to peptidyl aldehyde residues within collagen and elastin, thus initiating formation of the covalent cross-linkages that insolubilize theseContinue Reading
  • Mingjun Huang, Andrew Maynard, +4 authors William Gorham Rice
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1998 (First Publication: 1 April 1998)
  • Agents that target the two highly conserved Zn fingers of the human immunodeficiency virus (HIV) nucleocapsid p7 (NCp7) protein are under development as antivirals. These agents covalently modifyContinue Reading
  • W. G. Rice, David Clarkston Baker, +10 authors Jim A. Turpin
  • Biology, Medicine
  • Antimicrobial agents and chemotherapy
  • 1997 (First Publication: 1 February 1997)
  • The human immunodeficiency virus type 1 (HIV-1) nucleocapsid p7 protein contains two retrovirus-type zinc finger domains that are required for multiple phases of viral replication. Chelating residuesContinue Reading
  • Mark Cushman, Wiesław Marek Gołębiewski, +7 authors William Gorham Rice
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 1994 (First Publication: 1 September 1994)
  • Cosalane (3), a novel anti-HIV agent having a disalicylmethane unit linked to C-3 of cholestane by a three-carbon linker, was synthesized from commercially available starting materials by aContinue Reading
  • Jim A. Turpin, R. W. Jun. Buckheit, +12 authors W. G. Rice
  • Biology, Medicine
  • Antimicrobial agents and chemotherapy
  • 1998 (First Publication: 1 March 1998)
  • Nanomolar concentrations of temacrazine (1,4-bis[3-(6-oxo-6H-v-triazolo[4,5,1-de]acridin-5-yl)amino-propyl ]piperazine) were discovered to inhibit acute human immunodeficiency virus type 1 (HIV-1)Continue Reading