Injection of the opiate antagonist naloxone completely prevented the rise of serum prolactin induced by ether stress in intact male rats. Naloxone also led to a 50--95% inhibition of the marked elevation of plasma prolactin levels induced by suckling. These data suggest that endogenous opiates (endorphins) are involved in the stimulation of prolactin… (More)
The localization of various neuropeptides is described in the gut and in the hypothalamus in the rat. Evidence is given for the presence of material resembling corticotropin-like intermediate peptide in arcuate and periarcuate neurons, projecting to various hypothalamic nuclei, limbic areas and the thalamus. beta-Endorphin and glucagon decrease dopamine… (More)
Public health surveillance is essential for detecting and responding to infectious diseases and necessary for compliance with the revised International Health Regulations (IHR) 2005. To assess reporting capacities and compliance with IHR of all 50 states and Washington, DC, we sent a questionnaire to respective epidemiologists; 47 of 51 responded. Overall… (More)
No significant change in hypothalamic TRH content was found in rats during acute (5-240 min) exposure to cold (5 degrees C), in spite of rapid and sustained elevations in plasma TSH and thyroxine. Plasma PRL rose markedly in the first 15 min, but returned to normal thereafter. Chronic exposure to cold (32 days) was characterized by elevated plasma and… (More)
Public health surveillance (PHS) is at a tipping point, where the application of novel processes, technologies, and tools promise to vastly improve efficiency and effectiveness. Yet twentieth century, entrenched ideology and lack of training results in slow uptake and resistance to change. The term disruptive innovation - used to describe advances in… (More)
and reproduction in any medium, provided the original work is properly cited.
reproduction in any medium, provided the original work is properly cited. Objective To develop a toolset to monitor and assess laboratory biosafety program performance and cost Introduction Laboratory biosafety – a component of biosecurity – has specific elements that together, comprise a facility's capability to both protect employees and the surrounding… (More)
reproduction in any medium, provided the original work is properly cited. Objective To conceive and develop a model to identify gaps in public health surveillance performance and provide a toolset to assess interventions , cost, and return on investment (ROI). one of the eight core capacities is public health surveillance. In May 2012, despite a concerted… (More)